2021 American Athletic Conference Leaders Rushing Defense - From Opponent's 1 To 20 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 10 | 24 | 205 | 8.54 | 0 | 78 | 6 | 5 | 1 |
| 2 | Tulane | 10 | 35 | 176 | 5.03 | 0 | 23 | 6 | 6 | 3 |
| 3 | SMU | 12 | 37 | 176 | 4.76 | 0 | 31 | 5 | 6 | 4 |
| 4 | South Florida | 9 | 38 | 388 | 10.21 | 2 | 97 | 7 | 7 | 5 |
| 5 | UCF | 13 | 41 | 171 | 4.17 | 0 | 27 | 6 | 5 | 2 |
| 6 | Temple | 12 | 42 | 165 | 3.93 | 0 | 28 | 6 | 4 | 1 |
| 7 | Memphis | 12 | 43 | 133 | 3.09 | 0 | 18 | 5 | 3 | 0 |
| 8 | East Carolina | 12 | 48 | 357 | 7.44 | 1 | 90 | 11 | 9 | 4 |
| 9 | Cincinnati | 13 | 58 | 198 | 3.41 | 0 | 23 | 6 | 5 | 2 |
| 10 | Houston | 13 | 61 | 155 | 2.54 | 0 | 22 | 5 | 4 | 1 |
| 11 | Tulsa | 13 | 66 | 295 | 4.47 | 0 | 54 | 11 | 6 | 2 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||