2021 American Athletic Conference Leaders Yards From Scrimmage - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Recv Yards | TD | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cameron Carroll | Tulane | SO | RB | 2 | 71 | 25 | 3 | 24 | 96 | 4.0 | 48.0 |
| 2 | Ryan O'Keefe | UCF | JR | WR | 2 | 110 | 159 | 2 | 15 | 269 | 17.9 | 134.5 |
| 2 | Calvin Austin III | Memphis | SR | WR | 1 | 0 | 105 | 2 | 9 | 105 | 11.7 | 105.0 |
| 2 | Isaiah Bowser | UCF | SR | RB | 2 | 192 | 0 | 2 | 41 | 192 | 4.7 | 96.0 |
| 2 | Jerome Ford | Cincinnati | JR | RB | 2 | 143 | 12 | 2 | 39 | 155 | 4.0 | 77.5 |
| 2 | Dillon Gabriel | UCF | JR | QB | 1 | 18 | 17 | 2 | 11 | 35 | 3.2 | 35.0 |
| 2 | Jaren Mangham | S Florida | JR | RB | 2 | 55 | 1 | 2 | 14 | 56 | 4.0 | 28.0 |
| 8 | Ulysses Bentley IV | SMU | SO | RB | 1 | 153 | 13 | 1 | 22 | 166 | 7.5 | 166.0 |
| 8 | Danny Gray | SMU | SR | WR | 1 | 0 | 130 | 1 | 4 | 130 | 32.5 | 130.0 |
| 8 | Nathaniel Dell | Houston | SO | WR | 2 | 5 | 230 | 1 | 18 | 235 | 13.1 | 117.5 |
| 8 | Jsi Hatfield | ECU | SO | WR | 1 | 0 | 90 | 1 | 2 | 90 | 45.0 | 90.0 |
| 8 | Josh Johnson | Tulsa | SR | WR | 2 | -1 | 156 | 1 | 11 | 155 | 14.1 | 77.5 |
| 8 | Tyrick James | Tulane | JR | TE | 2 | 0 | 140 | 1 | 9 | 140 | 15.6 | 70.0 |
| 8 | Deneric Prince | Tulsa | JR | RB | 2 | 72 | 63 | 1 | 31 | 135 | 4.4 | 67.5 |
| 8 | Edward Saydee | Temple | FR | RB | 2 | 82 | 27 | 1 | 21 | 109 | 5.2 | 54.5 |
| 8 | Alec Pierce | Cincinnati | SR | WR | 2 | 0 | 103 | 1 | 7 | 103 | 14.7 | 51.5 |
| 8 | Shae Wyatt | Tulane | JR | WR | 2 | 0 | 98 | 1 | 7 | 98 | 14.0 | 49.0 |
| 8 | Alton McCaskill | Houston | FR | RB | 2 | 83 | 15 | 1 | 23 | 98 | 4.3 | 49.0 |
| 8 | Jaylon Robinson | UCF | JR | WR | 1 | 0 | 47 | 1 | 4 | 47 | 11.8 | 47.0 |
| 8 | Reggie Roberson, Jr. | SMU | SR | WR | 1 | 0 | 40 | 1 | 3 | 40 | 13.3 | 40.0 |
| 8 | Tanner Mordecai | SMU | JR | QB | 1 | 37 | 0 | 1 | 4 | 37 | 9.3 | 37.0 |
| 8 | Clayton Tune | Houston | JR | QB | 2 | 71 | 0 | 1 | 20 | 71 | 3.6 | 35.5 |
| 8 | Michael Pratt | Tulane | FR | QB | 2 | 71 | 0 | 1 | 26 | 71 | 2.7 | 35.5 |
| 8 | Jake Herslow | Houston | SR | WR | 2 | 0 | 63 | 1 | 6 | 63 | 10.5 | 31.5 |
| 8 | Anthony Watkins | Tulsa | SO | RB | 2 | 53 | 8 | 1 | 9 | 61 | 6.8 | 30.5 |
| 8 | Jaetavian Toles | Tulane | SR | WR | 2 | 10 | 42 | 1 | 4 | 52 | 13.0 | 26.0 |
| 8 | Jordan Kerley | SMU | SO | WR | 1 | 0 | 26 | 1 | 1 | 26 | 26.0 | 26.0 |
| 8 | Rashee Rice | SMU | JR | WR | 1 | 0 | 20 | 1 | 4 | 20 | 5.0 | 20.0 |
| 8 | Desmond Ridder | Cincinnati | SR | QB | 2 | 39 | 0 | 1 | 20 | 39 | 2.0 | 19.5 |
| 8 | Will Wallace | Tulane | JR | TE | 2 | 0 | 27 | 1 | 3 | 27 | 9.0 | 13.5 |
| 8 | Cannon Montgomery | Tulsa | SR | WR | 2 | 0 | 21 | 1 | 1 | 21 | 21.0 | 10.5 |
| 8 | Brandon Johnson | UCF | SR | WR | 2 | 0 | 16 | 1 | 3 | 16 | 5.3 | 8.0 |
| 8 | D'Wan Mathis | Temple | FR | QB | 1 | 6 | 0 | 1 | 9 | 6 | 0.7 | 6.0 |
| 8 | Seth Green | Houston | SR | TE | 2 | 0 | 9 | 1 | 1 | 9 | 9.0 | 4.5 |
| 8 | Holton Ahlers | ECU | JR | QB | 1 | 4 | 0 | 1 | 10 | 4 | 0.4 | 4.0 |