2021 Atlantic Coast Conference Leaders Total Offense - Games in December/January Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 1 | 232 | 194 | 64 | 426 | 6.66 | 426.0 |
| 1 | North Carolina | 1 | 128 | 205 | 50 | 333 | 6.66 | 333.0 |
| 3 | Pittsburgh | 2 | 216 | 443 | 127 | 659 | 5.19 | 329.5 |
| 4 | Wake Forest | 2 | 230 | 517 | 161 | 747 | 4.64 | 373.5 |
| 5 | Clemson | 1 | 128 | 187 | 73 | 315 | 4.32 | 315.0 |
| 6 | Virginia Tech | 1 | 122 | 137 | 67 | 259 | 3.87 | 259.0 |