2021 Atlantic Coast Conference Leaders Scoring Defense - Games in October Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 4 | 11 | 2 | 11 | 0 | 0 | 83 | 20.8 |
| 1 | Virginia Tech | 4 | 16 | 2 | 14 | 1 | 0 | 118 | 29.5 |
| 3 | Wake Forest | 4 | 18 | 3 | 17 | 0 | 0 | 134 | 33.5 |
| 4 | Clemson | 4 | 9 | 4 | 8 | 0 | 0 | 74 | 18.5 |
| 4 | Florida State | 4 | 11 | 4 | 8 | 1 | 0 | 88 | 22.0 |
| 6 | North Carolina State | 4 | 9 | 5 | 9 | 0 | 0 | 78 | 19.5 |
| 6 | Boston College | 4 | 12 | 5 | 12 | 0 | 1 | 101 | 25.3 |
| 6 | Louisville | 4 | 14 | 5 | 14 | 0 | 0 | 113 | 28.3 |
| 6 | North Carolina | 4 | 16 | 5 | 15 | 1 | 0 | 128 | 32.0 |
| 6 | Duke | 4 | 21 | 5 | 21 | 0 | 0 | 162 | 40.5 |
| 11 | Miami (Florida) | 3 | 13 | 6 | 13 | 0 | 0 | 109 | 36.3 |
| 12 | Virginia | 4 | 17 | 7 | 14 | 1 | 0 | 139 | 34.8 |
| 13 | Syracuse | 5 | 15 | 9 | 11 | 2 | 0 | 132 | 26.4 |
| 13 | Georgia Tech | 4 | 18 | 9 | 18 | 0 | 0 | 153 | 38.3 |