2021 Atlantic Coast Conference Leaders Passing Defense - From Opponent's 1 To 20 Yard Line through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 13 | 55 | 32 | 58.2 | 311 | 0 | 4 | 91.13 | 31 | 14 | 6 | 2 |
| 2 | Pittsburgh | 14 | 62 | 40 | 64.5 | 389 | 0 | 2 | 110.77 | 40 | 14 | 7 | 2 |
| 3 | Florida State | 8 | 25 | 17 | 68.0 | 177 | 0 | 1 | 119.47 | 33 | 9 | 3 | 2 |
| 3 | North Carolina State | 12 | 63 | 34 | 54.0 | 241 | 0 | 1 | 82.93 | 19 | 11 | 4 | 0 |
| 3 | Louisville | 10 | 33 | 20 | 60.6 | 267 | 0 | 1 | 122.51 | 33 | 12 | 9 | 3 |
| 3 | Virginia | 10 | 29 | 19 | 65.5 | 284 | 1 | 1 | 152.26 | 92 | 5 | 5 | 3 |
| 3 | Wake Forest | 11 | 45 | 28 | 62.2 | 309 | 0 | 1 | 115.46 | 30 | 15 | 7 | 2 |
| 3 | Georgia Tech | 11 | 31 | 21 | 67.7 | 314 | 0 | 1 | 146.37 | 51 | 10 | 8 | 4 |
| 3 | Miami (Florida) | 10 | 44 | 30 | 68.2 | 432 | 1 | 1 | 153.60 | 94 | 8 | 8 | 4 |
| 3 | Virginia Tech | 13 | 51 | 34 | 66.7 | 484 | 0 | 1 | 142.47 | 46 | 22 | 13 | 7 |
| 11 | Syracuse | 10 | 23 | 15 | 65.2 | 184 | 0 | 0 | 132.42 | 32 | 7 | 5 | 2 |
| 11 | North Carolina | 9 | 18 | 14 | 77.8 | 214 | 1 | 0 | 195.98 | 80 | 7 | 5 | 1 |
| 11 | Boston College | 9 | 26 | 15 | 57.7 | 225 | 0 | 0 | 130.38 | 54 | 8 | 5 | 2 |
| 11 | Duke | 10 | 37 | 23 | 62.2 | 284 | 0 | 0 | 126.64 | 39 | 14 | 9 | 3 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||