2021 Atlantic Coast Conference Leaders Passing Defense - On 3rd Down, 4-6 Yards To Go through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Boston College | 11 | 22 | 9 | 40.9 | 87 | 1 | 2 | 70.95 | 32 | 8 | 1 | 1 |
| 1 | Duke | 11 | 39 | 26 | 66.7 | 471 | 4 | 2 | 191.70 | 77 | 26 | 10 | 6 |
| 3 | Virginia Tech | 11 | 21 | 8 | 38.1 | 79 | 0 | 1 | 60.18 | 39 | 5 | 1 | 1 |
| 3 | Wake Forest | 11 | 26 | 14 | 53.8 | 139 | 1 | 1 | 103.76 | 30 | 10 | 3 | 1 |
| 3 | Louisville | 13 | 33 | 17 | 51.5 | 171 | 1 | 1 | 98.99 | 31 | 11 | 4 | 2 |
| 3 | Pittsburgh | 13 | 33 | 18 | 54.5 | 177 | 2 | 1 | 113.55 | 36 | 13 | 2 | 1 |
| 3 | North Carolina | 13 | 26 | 18 | 69.2 | 215 | 2 | 1 | 156.38 | 60 | 14 | 4 | 1 |
| 8 | North Carolina State | 12 | 30 | 13 | 43.3 | 97 | 3 | 0 | 103.49 | 24 | 8 | 1 | 0 |
| 8 | Syracuse | 11 | 27 | 17 | 63.0 | 174 | 2 | 0 | 141.53 | 30 | 12 | 4 | 2 |
| 8 | Virginia | 11 | 36 | 19 | 52.8 | 201 | 4 | 0 | 136.35 | 62 | 14 | 4 | 2 |
| 8 | Georgia Tech | 10 | 27 | 15 | 55.6 | 215 | 4 | 0 | 171.34 | 77 | 12 | 4 | 2 |
| 8 | Clemson | 13 | 36 | 18 | 50.0 | 217 | 2 | 0 | 118.97 | 58 | 13 | 4 | 2 |
| 8 | Florida State | 10 | 37 | 24 | 64.9 | 229 | 4 | 0 | 152.54 | 25 | 18 | 5 | 2 |
| 8 | Miami (Florida) | 11 | 32 | 18 | 56.3 | 267 | 4 | 0 | 167.59 | 94 | 14 | 5 | 3 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||