2021 Atlantic Coast Conference Leaders Rushing Defense - On 3rd Down through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 11 | 55 | 86 | 1.56 | 1 | 21 | 12 | 6 | 1 |
| 1 | Florida State | 12 | 78 | 193 | 2.47 | 1 | 31 | 27 | 10 | 1 |
| 3 | Pittsburgh | 14 | 76 | 26 | 0.34 | 2 | 23 | 18 | 5 | 1 |
| 4 | Clemson | 13 | 81 | 152 | 1.88 | 3 | 51 | 25 | 8 | 4 |
| 4 | North Carolina | 13 | 82 | 245 | 2.99 | 3 | 16 | 33 | 7 | 0 |
| 4 | Virginia | 12 | 72 | 267 | 3.71 | 3 | 26 | 24 | 13 | 5 |
| 4 | Virginia Tech | 13 | 78 | 322 | 4.13 | 3 | 21 | 33 | 14 | 1 |
| 8 | Syracuse | 12 | 82 | 198 | 2.41 | 4 | 47 | 29 | 10 | 2 |
| 9 | Louisville | 13 | 74 | 201 | 2.72 | 5 | 35 | 26 | 8 | 4 |
| 9 | Miami (Florida) | 12 | 66 | 283 | 4.29 | 5 | 71 | 27 | 9 | 5 |
| 9 | Georgia Tech | 12 | 76 | 334 | 4.39 | 5 | 59 | 31 | 11 | 2 |
| 12 | Boston College | 12 | 72 | 214 | 2.97 | 6 | 48 | 26 | 9 | 2 |
| 12 | Duke | 12 | 64 | 270 | 4.22 | 6 | 44 | 24 | 6 | 4 |
| 14 | Wake Forest | 14 | 93 | 236 | 2.54 | 7 | 58 | 31 | 11 | 2 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||