2021 Atlantic Coast Conference Leaders Interceptions - Games Lost Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jammie Robinson | FSU | SO | DB | 7 | 2 | 75 | 0 | 0.29 |
| 2 | Fentrell Cypress II | Virginia | SO | DB | 3 | 1 | 66 | 0 | 0.33 |
| 3 | Jermaine Waller | Va Tech | JR | DB | 6 | 2 | 37 | 1 | 0.33 |
| 4 | Jahfari Harvey | Miami (Fl) | FR | DL | 5 | 1 | 33 | 1 | 0.20 |
| 4 | Joey Blount | Virginia | SR | FS | 6 | 1 | 33 | 0 | 0.17 |
| 6 | Trey Franklin | Louisville | SO | DB | 7 | 1 | 32 | 0 | 0.14 |
| 7 | Qwynnterrio Cole | Louisville | SR | DB | 7 | 1 | 29 | 0 | 0.14 |
| 8 | Leonard Johnson | Duke | SR | CB | 8 | 1 | 26 | 0 | 0.13 |
| 9 | Nasir Peoples | Va Tech | SO | DB | 7 | 1 | 14 | 0 | 0.14 |
| 10 | Jaiden Woodbey | BC | JR | DB | 6 | 1 | 12 | 0 | 0.17 |
| 10 | Jeremiah Lewis | Duke | JR | CB | 9 | 1 | 12 | 0 | 0.11 |
| 12 | Corey Flagg, Jr. | Miami (Fl) | FR | LB | 5 | 1 | 9 | 0 | 0.20 |
| 13 | R.J. Oben | Duke | SO | DE | 9 | 1 | 8 | 0 | 0.11 |
| 14 | Dorian Strong | Va Tech | FR | DB | 7 | 1 | 7 | 0 | 0.14 |
| 15 | Darian Chestnut | Syracuse | FR | DB | 7 | 2 | 5 | 0 | 0.29 |
| 15 | Shyheim Battle | NC State | FR | CB | 3 | 1 | 5 | 0 | 0.33 |
| 15 | Travis Jay | FSU | FR | DB | 6 | 1 | 5 | 0 | 0.17 |
| 18 | Jason Simmons | Syracuse | SO | DB | 7 | 1 | 4 | 0 | 0.14 |
| 19 | Baylon Spector | Clemson | SR | LB | 3 | 1 | 3 | 0 | 0.33 |
| 19 | Kenderick Duncan | Louisville | JR | DB | 6 | 1 | 3 | 0 | 0.17 |