2021 Sun Belt Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Troy | 1 | 99 | 255 | 62 | 354 | 5.71 | 354.0 |
| 2 | Coastal Carolina | 1 | 172 | 238 | 68 | 410 | 6.03 | 410.0 |
| 2 | Louisiana-Lafayette | 1 | 170 | 265 | 68 | 435 | 6.40 | 435.0 |
| 4 | Texas State | 1 | 244 | 148 | 69 | 392 | 5.68 | 392.0 |
| 5 | South Alabama | 1 | 250 | 311 | 72 | 561 | 7.79 | 561.0 |
| 6 | Georgia Southern | 1 | 269 | 364 | 73 | 633 | 8.67 | 633.0 |
| 7 | Appalachian State | 1 | 175 | 200 | 76 | 375 | 4.93 | 375.0 |
| 8 | Arkansas State | 1 | 200 | 398 | 83 | 598 | 7.20 | 598.0 |
| 9 | Louisiana-Monroe | 2 | 237 | 738 | 139 | 975 | 7.01 | 487.5 |
| 10 | Georgia State | 2 | 367 | 659 | 149 | 1026 | 6.89 | 513.0 |