2021 Big 12 Conference Leaders Fumbles Lost - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | Kansas | 10 | 9 | 3 | 33.33 |
| 1 | Oklahoma State | 10 | 11 | 3 | 27.27 |
| 1 | Oklahoma | 11 | 14 | 3 | 21.43 |
| 4 | Iowa State | 11 | 15 | 4 | 26.67 |
| 5 | Texas Tech | 10 | 7 | 5 | 71.43 |
| 5 | Kansas State | 11 | 9 | 5 | 55.56 |
| 7 | Baylor | 11 | 13 | 7 | 53.85 |
| 7 | Texas | 10 | 13 | 7 | 53.85 |
| 7 | West Virginia | 12 | 19 | 7 | 36.84 |
| 10 | TCU | 10 | 18 | 9 | 50.00 |