2021 Big 12 Conference Leaders Rushing Offense - Games in December/January Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma | 1 | 43 | 322 | 7.49 | 3 | 43.00 | 322.00 |
| 2 | Texas Tech | 1 | 44 | 260 | 5.91 | 3 | 44.00 | 260.00 |
| 3 | Kansas State | 1 | 34 | 183 | 5.38 | 3 | 34.00 | 183.00 |
| 4 | Baylor | 2 | 74 | 341 | 4.61 | 1 | 37.00 | 170.50 |
| 5 | Oklahoma State | 2 | 84 | 300 | 3.57 | 1 | 42.00 | 150.00 |
| 6 | Iowa State | 1 | 21 | 66 | 3.14 | 0 | 21.00 | 66.00 |
| 6 | West Virginia | 1 | 27 | 66 | 2.44 | 1 | 27.00 | 66.00 |