2021 Big 12 Conference Leaders Total Offense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 10 | 1930 | 2208 | 738 | 4138 | 5.61 | 413.8 |
| 2 | West Virginia | 10 | 1433 | 2656 | 704 | 4089 | 5.81 | 408.9 |
| 3 | Oklahoma | 10 | 1833 | 2753 | 645 | 4586 | 7.11 | 458.6 |
| 4 | Baylor | 9 | 2028 | 2096 | 619 | 4124 | 6.66 | 458.2 |
| 5 | Texas Tech | 9 | 1670 | 2499 | 597 | 4169 | 6.98 | 463.2 |
| 6 | Kansas | 9 | 1298 | 1871 | 587 | 3169 | 5.40 | 352.1 |
| 7 | TCU | 9 | 1945 | 1859 | 586 | 3804 | 6.49 | 422.7 |
| 8 | Kansas State | 10 | 1844 | 1918 | 572 | 3762 | 6.58 | 376.2 |
| 9 | Iowa State | 8 | 1602 | 2094 | 501 | 3696 | 7.38 | 462.0 |
| 10 | Texas | 7 | 1715 | 1475 | 483 | 3190 | 6.60 | 455.7 |