2021 Big 12 Conference Leaders First Downs - Games Lost Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Kansas | 10 | 71 | 81 | 9 | 161 | 16.1 |
| 2 | TCU | 7 | 56 | 66 | 9 | 131 | 18.7 |
| 3 | Texas | 7 | 50 | 69 | 6 | 125 | 17.9 |
| 4 | West Virginia | 7 | 44 | 74 | 10 | 128 | 18.3 |
| 5 | Iowa State | 6 | 40 | 75 | 14 | 129 | 21.5 |
| 6 | Texas Tech | 6 | 38 | 58 | 12 | 108 | 18.0 |
| 7 | Kansas State | 5 | 33 | 43 | 5 | 81 | 16.2 |
| 8 | Oklahoma State | 2 | 13 | 23 | 6 | 42 | 21.0 |
| 9 | Oklahoma | 2 | 12 | 21 | 5 | 38 | 19.0 |
| 9 | Baylor | 2 | 12 | 12 | 2 | 26 | 13.0 |