2021 Big 12 Conference Leaders Rushing Defense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | TCU | 5 | 191 | 1316 | 6.89 | 22 | 38.20 | 263.20 |
| 2 | Oklahoma | 6 | 212 | 1022 | 4.82 | 9 | 35.33 | 170.33 |
| 3 | Kansas State | 6 | 213 | 813 | 3.82 | 5 | 35.50 | 135.50 |
| 4 | Oklahoma State | 7 | 214 | 412 | 1.93 | 4 | 30.57 | 58.86 |
| 5 | Iowa State | 7 | 234 | 960 | 4.10 | 9 | 33.43 | 137.14 |
| 6 | Texas Tech | 7 | 237 | 958 | 4.04 | 7 | 33.86 | 136.86 |
| 7 | Texas | 6 | 249 | 1405 | 5.64 | 16 | 41.50 | 234.17 |
| 8 | Kansas | 6 | 253 | 1566 | 6.19 | 22 | 42.17 | 261.00 |
| 9 | West Virginia | 7 | 256 | 1038 | 4.05 | 7 | 36.57 | 148.29 |
| 10 | Baylor | 7 | 269 | 810 | 3.01 | 6 | 38.43 | 115.71 |