2021 Big 12 Conference Leaders Opponent First Downs - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 22 | 20 | 5 | 47 | 11.8 |
| 2 | West Virginia | 4 | 28 | 37 | 5 | 70 | 17.5 |
| 3 | Baylor | 5 | 30 | 54 | 12 | 96 | 19.2 |
| 4 | Iowa State | 5 | 37 | 40 | 5 | 82 | 16.4 |
| 5 | Kansas State | 6 | 39 | 53 | 8 | 100 | 16.7 |
| 5 | Texas | 4 | 39 | 42 | 7 | 88 | 22.0 |
| 7 | Oklahoma | 6 | 41 | 77 | 5 | 123 | 20.5 |
| 8 | TCU | 4 | 42 | 36 | 8 | 86 | 21.5 |
| 9 | Texas Tech | 5 | 51 | 41 | 4 | 96 | 19.2 |
| 9 | Kansas | 4 | 51 | 43 | 5 | 99 | 24.8 |