2021 Big 12 Conference Leaders Scoring Defense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | TCU | 3 | 11 | 1 | 6 | 1 | 0 | 77 | 25.7 |
| 1 | Kansas | 3 | 16 | 1 | 16 | 0 | 0 | 115 | 38.3 |
| 3 | Kansas State | 4 | 9 | 2 | 7 | 0 | 0 | 67 | 16.8 |
| 3 | Oklahoma | 4 | 11 | 2 | 7 | 2 | 0 | 83 | 20.8 |
| 5 | Baylor | 4 | 7 | 3 | 7 | 0 | 0 | 58 | 14.5 |
| 5 | Texas Tech | 4 | 9 | 3 | 8 | 0 | 0 | 71 | 17.8 |
| 7 | West Virginia | 4 | 8 | 4 | 7 | 1 | 0 | 69 | 17.3 |
| 8 | Iowa State | 4 | 6 | 6 | 6 | 0 | 0 | 60 | 15.0 |
| 8 | Texas | 3 | 6 | 6 | 4 | 0 | 0 | 58 | 19.3 |
| 8 | Oklahoma State | 4 | 11 | 6 | 10 | 0 | 0 | 94 | 23.5 |