2021 Big 12 Conference Leaders Opponent First Downs - All Games through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 13 | 96 | 107 | 13 | 216 | 16.6 |
| 2 | West Virginia | 13 | 97 | 113 | 15 | 225 | 17.3 |
| 3 | TCU | 12 | 124 | 117 | 21 | 262 | 21.8 |
| 4 | Kansas | 12 | 151 | 122 | 14 | 287 | 23.9 |
| 5 | Kansas State | 13 | 93 | 124 | 16 | 233 | 17.9 |
| 6 | Oklahoma State | 14 | 69 | 125 | 25 | 219 | 15.6 |
| 7 | Texas | 12 | 117 | 127 | 17 | 261 | 21.8 |
| 8 | Baylor | 14 | 99 | 140 | 30 | 269 | 19.2 |
| 9 | Oklahoma | 13 | 101 | 152 | 21 | 274 | 21.1 |
| 10 | Texas Tech | 13 | 99 | 159 | 19 | 277 | 21.3 |