2021 Big 12 Conference Leaders Rushing Defense - When Winning By 15+ Pts through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Kansas | 1 | 9 | 52 | 5.78 | 1 | 16 | 2 | 2 | 0 |
| 2 | West Virginia | 2 | 37 | 70 | 1.89 | 1 | 25 | 6 | 3 | 2 |
| 3 | TCU | 2 | 56 | 212 | 3.79 | 3 | 24 | 9 | 5 | 1 |
| 4 | Texas Tech | 5 | 49 | 197 | 4.02 | 2 | 30 | 11 | 6 | 3 |
| 5 | Oklahoma State | 6 | 80 | 241 | 3.01 | 1 | 30 | 13 | 8 | 3 |
| 6 | Texas | 4 | 76 | 425 | 5.59 | 3 | 66 | 21 | 11 | 6 |
| 7 | Kansas State | 7 | 89 | 309 | 3.47 | 2 | 20 | 22 | 10 | 1 |
| 8 | Iowa State | 5 | 95 | 328 | 3.45 | 2 | 21 | 24 | 12 | 1 |
| 9 | Baylor | 6 | 98 | 343 | 3.50 | 4 | 28 | 25 | 17 | 1 |
| 10 | Oklahoma | 6 | 104 | 392 | 3.77 | 3 | 33 | 26 | 15 | 1 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||