2021 Big 12 Conference Leaders Yards From Scrimmage - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Recv Yards | TD | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Deuce Vaughn | Kansas St | SO | RB | 1 | 146 | -3 | 4 | 23 | 143 | 6.2 | 143.0 |
| 2 | Kennedy Brooks | Oklahoma | JR | RB | 1 | 142 | 24 | 3 | 17 | 166 | 9.8 | 166.0 |
| 2 | Tay Martin | Okla St | SR | WR | 2 | 0 | 192 | 3 | 19 | 192 | 10.1 | 96.0 |
| 4 | Malik Knowles | Kansas St | JR | WR | 1 | 4 | 42 | 2 | 4 | 46 | 11.5 | 46.0 |
| 4 | Tyquan Thornton | Baylor | SR | WR | 2 | -11 | 73 | 2 | 8 | 62 | 7.8 | 31.0 |
| 6 | Eric Gray | Oklahoma | JR | RB | 1 | 82 | 25 | 1 | 13 | 107 | 8.2 | 107.0 |
| 6 | Tahj Brooks | Texas Tech | SO | RB | 1 | 107 | 0 | 1 | 16 | 107 | 6.7 | 107.0 |
| 6 | SaRodorick Thompson | Texas Tech | JR | RB | 1 | 80 | 0 | 1 | 14 | 80 | 5.7 | 80.0 |
| 6 | Marvin Mims | Oklahoma | SO | WR | 1 | 0 | 57 | 1 | 2 | 57 | 28.5 | 57.0 |
| 6 | Monaray Baldwin | Baylor | FR | WR | 1 | 48 | 0 | 1 | 1 | 48 | 48.0 | 48.0 |
| 6 | Charlie Kolar | Iowa State | SR | TE | 1 | 0 | 33 | 1 | 4 | 33 | 8.3 | 33.0 |
| 6 | Jaden Bray | Okla St | FR | WR | 2 | 0 | 61 | 1 | 4 | 61 | 15.3 | 30.5 |
| 6 | Donovan Smith | Texas Tech | FR | QB | 1 | 30 | 0 | 1 | 5 | 30 | 6.0 | 30.0 |
| 6 | J.J. Sparkman | Texas Tech | FR | WR | 1 | 0 | 29 | 1 | 2 | 29 | 14.5 | 29.0 |
| 6 | Drew Estrada | Baylor | SR | WR | 2 | 1 | 47 | 1 | 9 | 48 | 5.3 | 24.0 |
| 6 | Ben Sims | Baylor | JR | TE | 2 | 0 | 34 | 1 | 4 | 34 | 8.5 | 17.0 |
| 6 | Dominic Richardson | Okla St | SO | RB | 2 | 5 | 8 | 1 | 10 | 13 | 1.3 | 6.5 |
| 6 | Drake Stoops | Oklahoma | JR | WR | 1 | 0 | 6 | 1 | 1 | 6 | 6.0 | 6.0 |
| 6 | Jarret Doege | WVU | SR | QB | 1 | -22 | 0 | 1 | 8 | -22 | -2.8 | -22.0 |