2021 Big 12 Conference Leaders Rushing - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Deuce Vaughn | Kansas St | SO | RB | 1 | 21 | 146 | 6.95 | 3 | 21.00 | 146.00 |
| 1 | Kennedy Brooks | Oklahoma | JR | RB | 1 | 14 | 142 | 10.14 | 3 | 14.00 | 142.00 |
| 3 | Tahj Brooks | Texas Tech | SO | RB | 1 | 16 | 107 | 6.69 | 1 | 16.00 | 107.00 |
| 3 | SaRodorick Thompson | Texas Tech | JR | RB | 1 | 14 | 80 | 5.71 | 1 | 14.00 | 80.00 |
| 3 | Monaray Baldwin | Baylor | FR | WR | 1 | 1 | 48 | 48.00 | 1 | 1.00 | 48.00 |
| 3 | Donovan Smith | Texas Tech | FR | QB | 1 | 5 | 30 | 6.00 | 1 | 5.00 | 30.00 |
| 3 | Dominic Richardson | Okla St | SO | RB | 2 | 8 | 5 | 0.63 | 1 | 4.00 | 2.50 |
| 3 | Jarret Doege | WVU | SR | QB | 1 | 8 | -22 | -2.75 | 1 | 8.00 | -22.00 |