2021 Big 12 Conference Leaders Tackles For Loss - Games in November Only through 01/10/2022
| Name | Team | Yr | Pos | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Eyioma Uwazurike | Iowa State | SR | DE | 4 | 3.5 | 36 | 0.88 |
| 2 | Jason Taylor II | Okla St | JR | S | 4 | 4.0 | 33 | 1.00 |
| 3 | Will McDonald IV | Iowa State | JR | DE | 4 | 5.0 | 30 | 1.25 |
| 3 | Nate Matlack | Kansas St | FR | DE | 4 | 4.0 | 30 | 1.00 |
| 5 | Daniel Green | Kansas St | JR | LB | 4 | 8.0 | 29 | 2.00 |
| 5 | Nik Bonitto | Oklahoma | JR | OLB | 3 | 6.0 | 29 | 2.00 |
| 7 | Malcolm Rodriguez | Okla St | SR | LB | 4 | 6.0 | 27 | 1.50 |
| 8 | Devin Harper | Okla St | SR | LB | 4 | 5.5 | 26 | 1.38 |
| 9 | Terrel Bernard | Baylor | SR | LB | 4 | 6.0 | 24 | 1.50 |
| 9 | Brock Martin | Okla St | SR | DE | 4 | 5.0 | 24 | 1.25 |
| 9 | Collin Oliver | Okla St | FR | DE | 4 | 5.0 | 24 | 1.25 |
| 12 | Tyler Lacy | Okla St | JR | DE | 4 | 4.5 | 23 | 1.13 |
| 13 | Akheem Mesidor | WVU | SO | DL | 4 | 3.0 | 22 | 0.75 |
| 14 | Jalen Pitre | Baylor | SR | S | 4 | 6.0 | 21 | 1.50 |
| 14 | Gabe Hall | Baylor | SO | DL | 4 | 5.0 | 21 | 1.25 |
| 16 | Blake Peterson | Iowa State | SO | DE | 4 | 2.0 | 20 | 0.50 |
| 16 | Malcolm Lee | Kansas | SR | DL | 4 | 1.0 | 20 | 0.25 |
| 18 | Ben Davis | Texas | SR | EDG | 4 | 3.0 | 19 | 0.75 |
| 19 | Dylan Horton | TCU | SR | DE | 4 | 4.0 | 18 | 1.00 |
| 19 | Key Lawrence | Oklahoma | SO | DB | 3 | 1.0 | 18 | 0.33 |
| 21 | Isaiah Thomas | Oklahoma | SR | DL | 3 | 2.5 | 17 | 0.83 |
| 22 | Perrion Winfrey | Oklahoma | SR | DL | 3 | 4.5 | 16 | 1.50 |
| 22 | Jalen Redmond | Oklahoma | SO | DL | 3 | 4.5 | 16 | 1.50 |
| 22 | Brian Asamoah | Oklahoma | JR | LB | 3 | 4.0 | 16 | 1.33 |
| 22 | Rich Miller | Kansas | JR | LB | 4 | 3.0 | 16 | 0.75 |
| 26 | Kyron Johnson | Kansas | SR | DE | 4 | 2.0 | 14 | 0.50 |
| 26 | Matt Jones | Baylor | SO | LB | 4 | 1.5 | 14 | 0.38 |
| 28 | Mike Rose | Iowa State | SR | LB | 4 | 5.5 | 13 | 1.38 |
| 29 | Gavin Potter | Kansas | JR | LB | 4 | 2.5 | 12 | 0.63 |
| 29 | Bryson Jackson | Baylor | SR | OLB | 4 | 1.5 | 12 | 0.38 |
| 29 | Jarrick Bernard-Converse | Okla St | SR | CB | 4 | 1.5 | 12 | 0.38 |
| 32 | Eric Monroe | Texas Tech | SR | DB | 3 | 3.0 | 11 | 1.00 |
| 32 | Isaiah Lee | Iowa State | JR | DT | 4 | 2.5 | 11 | 0.63 |
| 32 | Josh Landry | Baylor | JR | DT | 4 | 1.5 | 11 | 0.38 |
| 35 | Eli Huggins | Kansas St | SR | DT | 4 | 2.5 | 10 | 0.63 |
| 35 | Zion DeBose | Kansas | SR | DE | 4 | 2.0 | 10 | 0.50 |
| 35 | Jacoby Jones | Texas | SR | EDG | 1 | 1.0 | 10 | 1.00 |
| 35 | Raleigh Texada | Baylor | SR | CB | 4 | 1.0 | 10 | 0.25 |
| 39 | Kenny Logan Jr. | Kansas | JR | S | 4 | 3.0 | 9 | 0.75 |
| 39 | Tony Bradford Jr. | Texas Tech | JR | DL | 3 | 2.5 | 9 | 0.83 |
| 39 | Nook Bradford | TCU | JR | S | 4 | 1.0 | 9 | 0.25 |
| 42 | JT Woods | Baylor | SR | S | 4 | 4.0 | 8 | 1.00 |
| 42 | Reggie Stubblefield | Kansas St | SR | DB | 4 | 4.0 | 8 | 1.00 |
| 42 | Scottie Young | WVU | SR | S | 4 | 2.0 | 8 | 0.50 |
| 42 | Nate Betts | Kansas | SR | LB | 4 | 1.5 | 8 | 0.38 |
| 46 | Felix Anudike-Uzomah | Kansas St | SO | DE | 4 | 3.0 | 7 | 0.75 |
| 46 | Jett Bush | Texas | JR | LB | 4 | 2.5 | 7 | 0.63 |
| 46 | Kolby Harvell-Peel | Okla St | SR | S | 4 | 2.0 | 7 | 0.50 |
| 46 | C.J. Ceasar II | TCU | JR | CB | 4 | 2.0 | 7 | 0.50 |
| 46 | Tyree Wilson | Texas Tech | JR | DL | 3 | 1.5 | 7 | 0.50 |