2021 Big 12 Conference Leaders Passing - From Opponent's 20 to 1 Yard Line (Red Zone) through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jarret Doege | WVU | SR | QB | 12 | 58 | 31 | 53.4 | 277 | 15 | 1 | 175.46 | 20 | 15 | 6 | 0 |
| 1 | Brock Purdy | Iowa State | SR | QB | 12 | 38 | 23 | 60.5 | 209 | 13 | 0 | 219.63 | 20 | 13 | 5 | 0 |
| 1 | Casey Thompson | Texas | JR | QB | 10 | 36 | 23 | 63.9 | 200 | 13 | 1 | 224.17 | 20 | 12 | 3 | 0 |
| 1 | Spencer Rattler | Oklahoma | SO | QB | 6 | 34 | 26 | 76.5 | 184 | 10 | 0 | 218.99 | 20 | 9 | 1 | 0 |
| 1 | Spencer Sanders | Okla St | JR | QB | 12 | 41 | 20 | 48.8 | 153 | 13 | 1 | 179.88 | 20 | 8 | 3 | 0 |
| 1 | Max Duggan | TCU | JR | QB | 10 | 31 | 18 | 58.1 | 148 | 8 | 2 | 170.43 | 20 | 8 | 4 | 0 |
| 1 | Jason Bean | Kansas | JR | QB | 6 | 25 | 10 | 40.0 | 103 | 5 | 2 | 124.61 | 20 | 3 | 3 | 0 |
| 1 | Chandler Morris | TCU | FR | QB | 3 | 9 | 5 | 55.6 | 49 | 3 | 0 | 211.29 | 20 | 3 | 2 | 0 |
| 9 | Jalon Daniels | Kansas | SO | QB | 5 | 21 | 12 | 57.1 | 103 | 6 | 2 | 173.57 | 19 | 7 | 2 | 0 |
| 10 | Gerry Bohanon | Baylor | JR | QB | 10 | 32 | 24 | 75.0 | 168 | 11 | 1 | 226.29 | 18 | 10 | 1 | 0 |
| 10 | Donovan Smith | Texas Tech | FR | QB | 3 | 12 | 9 | 75.0 | 77 | 4 | 0 | 238.90 | 18 | 3 | 2 | 0 |
| 10 | Hudson Card | Texas | FR | QB | 4 | 7 | 7 | 100.0 | 63 | 3 | 0 | 317.03 | 18 | 3 | 1 | 0 |
| 13 | Caleb Williams | Oklahoma | FR | QB | 9 | 38 | 28 | 73.7 | 222 | 15 | 0 | 253.01 | 17 | 14 | 3 | 0 |
| 13 | Henry Colombi | Texas Tech | SR | QB | 5 | 22 | 11 | 50.0 | 72 | 2 | 0 | 107.49 | 17 | 5 | 1 | 0 |
| 15 | Miles Kendrick | Kansas | SR | QB | 1 | 2 | 2 | 100.0 | 27 | 2 | 0 | 543.40 | 14 | 2 | 0 | 0 |
| 16 | Blake Shapen | Baylor | FR | QB | 3 | 17 | 9 | 52.9 | 46 | 4 | 0 | 153.32 | 13 | 2 | 0 | 0 |
| 16 | Hunter Dekkers | Iowa State | FR | QB | 2 | 2 | 2 | 100.0 | 25 | 2 | 0 | 535.00 | 13 | 2 | 0 | 0 |
| 18 | Skylar Thompson | Kansas St | SR | QB | 7 | 34 | 21 | 61.8 | 113 | 7 | 0 | 157.63 | 12 | 6 | 0 | 0 |
| 18 | Tyler Shough | Texas Tech | JR | QB | 4 | 17 | 12 | 70.6 | 66 | 3 | 0 | 161.44 | 12 | 2 | 0 | 0 |
| 18 | Shane Illingworth | Okla St | SO | QB | 2 | 6 | 3 | 50.0 | 19 | 3 | 0 | 241.60 | 12 | 1 | 0 | 0 |
| 21 | Will Howard | Kansas St | SO | QB | 3 | 4 | 1 | 25.0 | 11 | 0 | 0 | 48.10 | 11 | 1 | 0 | 0 |
| 22 | Garrett Greene | WVU | FR | QB | 2 | 3 | 3 | 100.0 | 20 | 0 | 0 | 156.00 | 10 | 1 | 0 | 0 |
| 23 | Ralph Rucker | Oklahoma | FR | QB | 1 | 1 | 1 | 100.0 | 8 | 0 | 0 | 167.20 | 8 | 0 | 0 | 0 |
| 24 | Tyquan Thornton | Baylor | SR | WR | 1 | 1 | 1 | 100.0 | 6 | 1 | 0 | 480.40 | 6 | 0 | 0 | 0 |
| 25 | Matthew Downing | TCU | JR | QB | 1 | 2 | 1 | 50.0 | 5 | 0 | 0 | 71.00 | 5 | 1 | 0 | 0 |
| 26 | Jaren Lewis | Kansas St | SO | QB | 1 | 1 | 1 | 100.0 | 2 | 0 | 0 | 116.80 | 2 | 0 | 0 | 0 |
| 27 | Jacob Zeno | Baylor | SO | QB | 1 | 1 | 0 | 0.0 | 0 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 |
| 27 | John Paul Richardson | Okla St | FR | WR | 1 | 1 | 0 | 0.0 | 0 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 |
| 27 | Taye Barber | TCU | SR | WR | 1 | 1 | 0 | 0.0 | 0 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | ||||||||||||||||