2021 Conference USA Leaders First Downs - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Marshall | 1 | 15 | 22 | 1 | 38 | 38.0 |
| 2 | Old Dominion | 1 | 19 | 10 | 3 | 32 | 32.0 |
| 2 | Florida Atlantic | 1 | 15 | 15 | 2 | 32 | 32.0 |
| 4 | Rice | 1 | 16 | 12 | 3 | 31 | 31.0 |
| 5 | North Texas | 1 | 17 | 10 | 2 | 29 | 29.0 |
| 6 | Louisiana Tech | 1 | 9 | 14 | 2 | 25 | 25.0 |
| 6 | Western Kentucky | 1 | 6 | 18 | 1 | 25 | 25.0 |
| 8 | Charlotte | 1 | 16 | 6 | 2 | 24 | 24.0 |
| 8 | UTEP | 1 | 14 | 7 | 3 | 24 | 24.0 |
| 10 | Southern Mississippi | 1 | 13 | 8 | 1 | 22 | 22.0 |
| 10 | Florida International | 1 | 10 | 12 | 0 | 22 | 22.0 |
| 12 | UTSA | 1 | 5 | 15 | 0 | 20 | 20.0 |
| 13 | Middle Tennessee | 1 | 8 | 11 | 0 | 19 | 19.0 |
| 13 | UAB | 1 | 5 | 14 | 0 | 19 | 19.0 |