2021 Conference USA Leaders Interceptions - Games in October Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee State | 4 | 10 | 169 | 1 | 2.50 |
| 2 | UTSA | 4 | 7 | 146 | 3 | 1.75 |
| 3 | UAB | 4 | 4 | 126 | 1 | 1.00 |
| 4 | Marshall | 4 | 6 | 93 | 0 | 1.50 |
| 5 | Florida Atlantic | 4 | 5 | 46 | 0 | 1.25 |
| 6 | Charlotte | 4 | 3 | 41 | 1 | 0.75 |
| 7 | Louisiana Tech | 4 | 2 | 39 | 0 | 0.50 |
| 8 | Western Kentucky | 5 | 4 | 34 | 0 | 0.80 |
| 9 | Old Dominion | 4 | 3 | 31 | 0 | 0.75 |
| 10 | North Texas | 4 | 1 | 23 | 0 | 0.25 |
| 11 | Rice | 4 | 5 | 7 | 0 | 1.25 |
| 12 | Southern Miss | 4 | 2 | 0 | 0 | 0.50 |
| 13 | UTEP | 4 | 5 | -1 | 0 | 1.25 |