2021 Conference USA Leaders Penalties - Games in October Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 4 | 14 | 152 | 3.5 | 38.0 |
| 2 | Florida International | 4 | 22 | 214 | 5.5 | 53.5 |
| 3 | Charlotte | 4 | 25 | 202 | 6.3 | 50.5 |
| 3 | Florida Atlantic | 4 | 25 | 230 | 6.3 | 57.5 |
| 5 | Rice | 4 | 26 | 213 | 6.5 | 53.3 |
| 5 | Louisiana Tech | 4 | 26 | 224 | 6.5 | 56.0 |
| 7 | Marshall | 4 | 27 | 222 | 6.8 | 55.5 |
| 7 | Middle Tennessee | 4 | 27 | 245 | 6.8 | 61.3 |
| 9 | Western Kentucky | 5 | 36 | 304 | 7.2 | 60.8 |
| 10 | UTEP | 4 | 30 | 286 | 7.5 | 71.5 |
| 11 | Old Dominion | 4 | 31 | 288 | 7.8 | 72.0 |
| 12 | UAB | 4 | 38 | 379 | 9.5 | 94.8 |
| 13 | North Texas | 4 | 39 | 370 | 9.8 | 92.5 |
| 14 | Southern Mississippi | 4 | 44 | 353 | 11.0 | 88.3 |