2021 Conference USA Leaders Passing Offense - Games in August/September Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Marshall | 4 | 164 | 105 | 64.0 | 1529 | 9.3 | 6 | 6 | 147.08 | 41.0 | 382.3 |
| 2 | UTSA | 4 | 139 | 91 | 65.5 | 1072 | 7.7 | 6 | 2 | 141.62 | 34.8 | 268.0 |
| 3 | Western Kentucky | 3 | 120 | 88 | 73.3 | 1278 | 10.7 | 14 | 2 | 197.96 | 40.0 | 426.0 |
| 3 | Middle Tennessee | 4 | 136 | 88 | 64.7 | 1101 | 8.1 | 12 | 2 | 158.90 | 34.0 | 275.3 |
| 5 | Louisiana Tech | 4 | 132 | 84 | 63.6 | 1076 | 8.2 | 9 | 3 | 150.07 | 33.0 | 269.0 |
| 6 | Florida Atlantic | 4 | 141 | 79 | 56.0 | 972 | 6.9 | 7 | 1 | 128.90 | 35.3 | 243.0 |
| 7 | North Texas | 4 | 152 | 75 | 49.3 | 757 | 5.0 | 4 | 5 | 93.28 | 38.0 | 189.3 |
| 8 | Charlotte | 4 | 119 | 72 | 60.5 | 989 | 8.3 | 9 | 2 | 151.91 | 29.8 | 247.3 |
| 9 | Old Dominion | 4 | 134 | 71 | 53.0 | 696 | 5.2 | 4 | 4 | 100.50 | 33.5 | 174.0 |
| 10 | Florida International | 4 | 120 | 65 | 54.2 | 1121 | 9.3 | 8 | 3 | 149.64 | 30.0 | 280.3 |
| 11 | Rice | 4 | 101 | 63 | 62.4 | 712 | 7.0 | 3 | 7 | 117.54 | 25.3 | 178.0 |
| 12 | UTEP | 4 | 98 | 56 | 57.1 | 957 | 9.8 | 6 | 6 | 147.13 | 24.5 | 239.3 |
| 13 | Southern Mississippi | 4 | 104 | 54 | 51.9 | 570 | 5.5 | 4 | 5 | 101.03 | 26.0 | 142.5 |
| 14 | UAB | 4 | 81 | 53 | 65.4 | 891 | 11.0 | 9 | 4 | 184.62 | 20.3 | 222.8 |