2021 Conference USA Leaders Total Offense - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 8 | 1099 | 2114 | 525 | 3213 | 6.12 | 401.6 |
| 2 | Western Kentucky | 6 | 631 | 2540 | 440 | 3171 | 7.21 | 528.5 |
| 3 | Charlotte | 7 | 848 | 2005 | 467 | 2853 | 6.11 | 407.6 |
| 4 | Marshall | 6 | 1009 | 1813 | 425 | 2822 | 6.64 | 470.3 |
| 5 | UTSA | 7 | 1343 | 1475 | 486 | 2818 | 5.80 | 402.6 |
| 6 | Middle Tennessee | 7 | 978 | 1764 | 506 | 2742 | 5.42 | 391.7 |
| 7 | UAB | 6 | 1144 | 1313 | 370 | 2457 | 6.64 | 409.5 |
| 8 | Florida International | 6 | 607 | 1790 | 384 | 2397 | 6.24 | 399.5 |
| 9 | Florida Atlantic | 5 | 906 | 1413 | 324 | 2319 | 7.16 | 463.8 |
| 10 | North Texas | 5 | 1321 | 968 | 387 | 2289 | 5.91 | 457.8 |
| 11 | Old Dominion | 5 | 937 | 1270 | 375 | 2207 | 5.89 | 441.4 |
| 12 | Rice | 5 | 747 | 1105 | 338 | 1852 | 5.48 | 370.4 |
| 13 | Louisiana Tech | 5 | 592 | 1210 | 340 | 1802 | 5.30 | 360.4 |
| 14 | Southern Mississippi | 6 | 800 | 959 | 372 | 1759 | 4.73 | 293.2 |