2021 Conference USA Leaders Turnover Margin - Games at Home Only through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | UTSA | 7 | 7 | 9 | 16 | 1 | 4 | 5 | 11 | 1.57 |
| 2 | Florida Atlantic | 6 | 1 | 7 | 8 | 5 | 1 | 6 | 2 | 0.33 |
| 3 | UAB | 5 | 7 | 4 | 11 | 3 | 4 | 7 | 4 | 0.80 |
| 3 | UTEP | 6 | 3 | 6 | 9 | 4 | 3 | 7 | 2 | 0.33 |
| 5 | Middle Tennessee | 5 | 11 | 8 | 19 | 5 | 3 | 8 | 11 | 2.20 |
| 5 | Western Kentucky | 6 | 4 | 12 | 16 | 2 | 6 | 8 | 8 | 1.33 |
| 5 | Florida International | 6 | 2 | 1 | 3 | 4 | 4 | 8 | -5 | -0.83 |
| 8 | North Texas | 6 | 7 | 3 | 10 | 2 | 7 | 9 | 1 | 0.17 |
| 9 | Charlotte | 6 | 4 | 1 | 5 | 5 | 5 | 10 | -5 | -0.83 |
| 10 | Southern Mississippi | 6 | 5 | 5 | 10 | 6 | 5 | 11 | -1 | -0.17 |
| 10 | Marshall | 6 | 4 | 3 | 7 | 3 | 8 | 11 | -4 | -0.67 |
| 12 | Old Dominion | 6 | 5 | 3 | 8 | 6 | 6 | 12 | -4 | -0.67 |
| 12 | Louisiana Tech | 6 | 4 | 4 | 8 | 5 | 7 | 12 | -4 | -0.67 |
| 14 | Rice | 6 | 2 | 10 | 12 | 4 | 9 | 13 | -1 | -0.17 |