2021 Conference USA Leaders Rushing Defense - On 4th Down through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 7 | 8 | -7 | -0.88 | 0 | 8 | 3 | 0 | 0 |
| 2 | UAB | 7 | 11 | 31 | 2.82 | 0 | 30 | 4 | 1 | 1 |
| 3 | North Texas | 9 | 11 | 0 | 0.00 | 0 | 3 | 5 | 0 | 0 |
| 3 | Rice | 5 | 8 | 22 | 2.75 | 0 | 7 | 5 | 0 | 0 |
| 3 | Louisiana Tech | 8 | 12 | 30 | 2.50 | 0 | 16 | 5 | 2 | 0 |
| 6 | UTSA | 8 | 10 | 22 | 2.20 | 1 | 12 | 6 | 1 | 0 |
| 6 | Middle Tennessee | 9 | 13 | 41 | 3.15 | 2 | 40 | 6 | 1 | 1 |
| 8 | Florida Atlantic | 5 | 13 | 12 | 0.92 | 0 | 9 | 7 | 0 | 0 |
| 8 | Florida International | 5 | 8 | 18 | 2.25 | 0 | 4 | 7 | 0 | 0 |
| 8 | Old Dominion | 11 | 18 | 35 | 1.94 | 0 | 27 | 7 | 2 | 2 |
| 8 | UTEP | 11 | 17 | 50 | 2.94 | 3 | 19 | 7 | 2 | 0 |
| 12 | Western Kentucky | 10 | 15 | 56 | 3.73 | 1 | 24 | 9 | 1 | 1 |
| 13 | Marshall | 7 | 14 | 83 | 5.93 | 1 | 41 | 10 | 2 | 2 |
| 14 | Charlotte | 8 | 15 | 59 | 3.93 | 0 | 13 | 12 | 2 | 0 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||