2021 Conference USA Leaders Rushing Defense - On 3rd Down, 4-6 Yards To Go through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | UTSA | 9 | 13 | 35 | 2.69 | 0 | 9 | 6 | 0 | 0 |
| 2 | UTEP | 7 | 15 | 17 | 1.13 | 0 | 22 | 4 | 1 | 1 |
| 2 | North Texas | 9 | 16 | 28 | 1.75 | 0 | 10 | 6 | 1 | 0 |
| 2 | Southern Mississippi | 6 | 9 | 31 | 3.44 | 0 | 12 | 4 | 1 | 0 |
| 2 | Western Kentucky | 5 | 13 | 44 | 3.38 | 0 | 21 | 4 | 1 | 1 |
| 2 | Marshall | 7 | 16 | 45 | 2.81 | 1 | 14 | 3 | 1 | 0 |
| 2 | Charlotte | 9 | 18 | 98 | 5.44 | 2 | 30 | 8 | 1 | 1 |
| 8 | Rice | 10 | 19 | 8 | 0.42 | 2 | 13 | 3 | 2 | 0 |
| 8 | Louisiana Tech | 8 | 17 | 31 | 1.82 | 1 | 14 | 5 | 2 | 0 |
| 8 | Florida Atlantic | 6 | 14 | 93 | 6.64 | 1 | 31 | 5 | 2 | 2 |
| 8 | Old Dominion | 7 | 12 | 93 | 7.75 | 0 | 56 | 8 | 2 | 1 |
| 12 | Florida International | 7 | 17 | 69 | 4.06 | 1 | 11 | 9 | 3 | 0 |
| 13 | UAB | 8 | 18 | 89 | 4.94 | 0 | 24 | 7 | 4 | 3 |
| 14 | Middle Tennessee | 10 | 17 | 110 | 6.47 | 0 | 21 | 9 | 5 | 1 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||