2021 Conference USA Leaders All Purpose - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Beanie Bishop | Western Ky | SO | DB | 2 | 0 | 0 | 0 | 72 | 3 | 72 | 24.0 | 36.0 |
| 2 | Lexington Joseph | FIU | SO | RB | 1 | 9 | 0 | 0 | 70 | 6 | 79 | 13.2 | 79.0 |
| 3 | Sean Fresch | Rice | FR | CB | 2 | 0 | 0 | 16 | 68 | 5 | 84 | 16.8 | 42.0 |
| 4 | D'Marcus Adams | FAU | SO | WR | 1 | 0 | 85 | 0 | 61 | 5 | 146 | 29.2 | 146.0 |
| 5 | Stone Smartt | ODU | SR | QB | 1 | 1 | 26 | 0 | 52 | 7 | 79 | 11.3 | 79.0 |
| 6 | Bub Means | La Tech | FR | WR | 2 | 0 | 189 | 0 | 39 | 10 | 228 | 22.8 | 114.0 |
| 7 | Camron Harrell | USM | JR | DB | 1 | 0 | 0 | 0 | 37 | 2 | 37 | 18.5 | 37.0 |
| 8 | Shadrick Byrd | Charlotte | SO | RB | 2 | 47 | 13 | 0 | 33 | 22 | 93 | 4.2 | 46.5 |
| 9 | Antavious Willis | USM | FR | DB | 1 | 0 | 0 | 0 | 22 | 1 | 22 | 22.0 | 22.0 |
| 10 | Jaylin Lane | MTSU | FR | WR | 1 | 0 | 30 | 0 | 18 | 5 | 48 | 9.6 | 48.0 |
| 11 | Jordan Myers | Rice | SR | TE | 2 | 64 | 30 | 0 | 16 | 24 | 110 | 4.6 | 55.0 |
| 12 | LaMareon James | ODU | FR | CB | 1 | 0 | 0 | 0 | 12 | 1 | 12 | 12.0 | 12.0 |