2021 Conference USA Leaders Tackles - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Solo | Assisted | Total | Total/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Antwon Kincade | Western Ky | SR | DB | 2 | 11 | 10 | 21 | 10.50 |
| 2 | Ken Robinson | UTSA | SO | CB | 2 | 10 | 4 | 14 | 7.00 |
| 2 | Demetrius Cain | Western Ky | SR | LB | 2 | 10 | 3 | 13 | 6.50 |
| 4 | Jason Henderson | ODU | FR | LB | 1 | 9 | 4 | 13 | 13.00 |
| 4 | Antonio Parks | UTSA | SR | S | 2 | 9 | 1 | 10 | 5.00 |
| 6 | Terry Jones | ODU | FR | S | 1 | 8 | 4 | 12 | 12.00 |
| 6 | Brandon Drayton | Marshall | SR | S | 1 | 8 | 2 | 10 | 10.00 |
| 6 | Jordan Young | ODU | SR | LB | 1 | 8 | 2 | 10 | 10.00 |
| 6 | Denzel Feaster | UTSA | SR | ILB | 2 | 8 | 2 | 10 | 5.00 |
| 6 | Rashad Wisdom | UTSA | JR | S | 2 | 8 | 1 | 9 | 4.50 |
| 11 | DeAngelo Malone | Western Ky | SR | DE | 2 | 7 | 8 | 15 | 7.50 |
| 11 | A.J. Brathwaite, Jr. | Western Ky | SO | DB | 2 | 7 | 6 | 13 | 6.50 |
| 11 | Breon Hayward | UTEP | JR | LB | 1 | 7 | 4 | 11 | 11.00 |
| 11 | Miguel Edwards | Western Ky | SO | DB | 2 | 7 | 4 | 11 | 5.50 |
| 11 | Antonio Moultrie | UAB | JR | DL | 1 | 7 | 2 | 9 | 9.00 |
| 11 | Sean-Thomas Faulkner | N Texas | JR | LB | 1 | 7 | 2 | 9 | 9.00 |
| 11 | Nazeeh Johnson | Marshall | SR | S | 1 | 7 | 0 | 7 | 7.00 |
| 11 | Corey Mayfield Jr. | UTSA | SR | CB | 2 | 7 | 0 | 7 | 3.50 |
| 19 | Tyrice Knight | UTEP | JR | LB | 1 | 6 | 9 | 15 | 15.00 |
| 19 | R'Tarriun Johnson | ODU | JR | S | 1 | 6 | 7 | 13 | 13.00 |
| 21 | KD Davis | N Texas | JR | LB | 1 | 5 | 9 | 14 | 14.00 |
| 21 | Jahmal Sam | UTSA | SO | S | 1 | 5 | 2 | 7 | 7.00 |
| 21 | Juwuan Jones | Western Ky | JR | DE | 2 | 5 | 2 | 7 | 3.50 |
| 21 | Abraham Beauplan | Marshall | JR | LB | 1 | 5 | 1 | 6 | 6.00 |
| 21 | Tre Hawkins III | ODU | JR | CB | 1 | 5 | 1 | 6 | 6.00 |
| 21 | DeShawn Gaddie | N Texas | SO | DB | 1 | 5 | 1 | 6 | 6.00 |
| 21 | Dennis Barnes | UTEP | JR | DB | 1 | 5 | 0 | 5 | 5.00 |
| 21 | Eli Neal | Marshall | SO | LB | 1 | 5 | 0 | 5 | 5.00 |
| 21 | Cory McCoy | Marshall | SR | S | 1 | 5 | 0 | 5 | 5.00 |
| 30 | Jamal Ligon | UTSA | SO | ILB | 2 | 4 | 6 | 10 | 5.00 |
| 30 | Brodric Martin | Western Ky | JR | DT | 2 | 4 | 6 | 10 | 5.00 |
| 30 | Kahlef Hailassie | Western Ky | SO | DB | 2 | 4 | 5 | 9 | 4.50 |
| 30 | Larry Nixon III | N Texas | SO | LB | 1 | 4 | 4 | 8 | 8.00 |
| 30 | Johnathan Butler | MTSU | JR | LB | 1 | 4 | 3 | 7 | 7.00 |
| 30 | Tyreke Davis | N Texas | SR | LB | 1 | 4 | 3 | 7 | 7.00 |
| 30 | Gregory Grate | MTSU | JR | S | 1 | 4 | 2 | 6 | 6.00 |
| 30 | Clarence Hicks | UTSA | SR | OLB | 2 | 4 | 2 | 6 | 3.00 |
| 30 | Roger Cray | ODU | SR | CB | 1 | 4 | 1 | 5 | 5.00 |
| 30 | Reed Blankenship | MTSU | SR | S | 1 | 4 | 0 | 4 | 4.00 |
| 30 | Micah Abraham | Marshall | SO | DB | 1 | 4 | 0 | 4 | 4.00 |
| 41 | Jaden Hunter | Western Ky | JR | DE | 2 | 3 | 8 | 11 | 5.50 |
| 41 | DQ Thomas | MTSU | SR | LB | 1 | 3 | 5 | 8 | 8.00 |
| 41 | Kelechi Nwachuku | UTSA | JR | S | 2 | 3 | 4 | 7 | 3.50 |
| 41 | Tyson Wilson | UTEP | SO | DB | 1 | 3 | 3 | 6 | 6.00 |
| 41 | Owen Porter | Marshall | SO | DL | 1 | 3 | 3 | 6 | 6.00 |
| 41 | Dominique Bradshaw | Western Ky | JR | DB | 2 | 3 | 3 | 6 | 3.00 |
| 41 | Charlie Gray | Marshall | JR | LB | 1 | 3 | 2 | 5 | 5.00 |
| 41 | Steven Gilmore | Marshall | JR | DB | 1 | 3 | 2 | 5 | 5.00 |
| 41 | Keelan Crosby | N Texas | SO | DB | 1 | 3 | 2 | 5 | 5.00 |
| 41 | Walter Neil Jr. | UTEP | SR | CB | 1 | 3 | 1 | 4 | 4.00 |