2021 Conference USA Leaders Tackles - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Solo | Assisted | Total | Total/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Antonio Moultrie | UAB | JR | DL | 2 | 9 | 7 | 16 | 8.00 |
| 2 | Brandon Drayton | Marshall | SR | S | 1 | 8 | 2 | 10 | 10.00 |
| 2 | Antwon Kincade | Western Ky | SR | DB | 1 | 8 | 2 | 10 | 10.00 |
| 2 | Tre Hawkins III | ODU | JR | CB | 1 | 8 | 1 | 9 | 9.00 |
| 5 | Jay Stanley | USM | SO | DB | 1 | 7 | 2 | 9 | 9.00 |
| 5 | Nazeeh Johnson | Marshall | SR | S | 1 | 7 | 0 | 7 | 7.00 |
| 7 | Antonio Montero | Rice | JR | LB | 2 | 6 | 15 | 21 | 10.50 |
| 7 | Malik Shorts | USM | SO | DB | 1 | 6 | 4 | 10 | 10.00 |
| 7 | Elijah Garcia | Rice | SR | DL | 2 | 6 | 4 | 10 | 5.00 |
| 7 | Denzel Feaster | UTSA | SR | ILB | 1 | 6 | 2 | 8 | 8.00 |
| 7 | Antonio Parks | UTSA | SR | S | 1 | 6 | 0 | 6 | 6.00 |
| 12 | Trey Schuman | Rice | JR | DE | 2 | 5 | 9 | 14 | 7.00 |
| 12 | Myron Morrison | Rice | FR | LB | 2 | 5 | 9 | 14 | 7.00 |
| 12 | Treshawn Chamberlain | Rice | JR | LB | 2 | 5 | 7 | 12 | 6.00 |
| 12 | Naeem Smith | Rice | SR | S | 2 | 5 | 7 | 12 | 6.00 |
| 12 | Kenneth Orji | Rice | JR | RSH | 2 | 5 | 4 | 9 | 4.50 |
| 12 | Keondre Swoopes | UAB | JR | S | 2 | 5 | 3 | 8 | 4.00 |
| 12 | Jordan Dunbar | Rice | FR | CB | 2 | 5 | 3 | 8 | 4.00 |
| 12 | Ken Robinson | UTSA | SO | CB | 1 | 5 | 2 | 7 | 7.00 |
| 12 | Abraham Beauplan | Marshall | JR | LB | 1 | 5 | 1 | 6 | 6.00 |
| 12 | Eli Neal | Marshall | SO | LB | 1 | 5 | 0 | 5 | 5.00 |
| 12 | Cory McCoy | Marshall | SR | S | 1 | 5 | 0 | 5 | 5.00 |
| 23 | Noah Wilder | UAB | SR | LB | 2 | 4 | 10 | 14 | 7.00 |
| 23 | Jordan Young | ODU | SR | LB | 1 | 4 | 5 | 9 | 9.00 |
| 23 | DeAngelo Malone | Western Ky | SR | DE | 1 | 4 | 5 | 9 | 9.00 |
| 23 | Will Boler | UAB | JR | S | 2 | 4 | 4 | 8 | 4.00 |
| 23 | Kaleb Oliver | Western Ky | JR | DB | 1 | 4 | 3 | 7 | 7.00 |
| 23 | Alex Wright | UAB | JR | OLB | 2 | 4 | 3 | 7 | 3.50 |
| 23 | Gabe Taylor | Rice | FR | DB | 2 | 4 | 2 | 6 | 3.00 |
| 23 | Deshon Hall | La Tech | SO | DL | 1 | 4 | 1 | 5 | 5.00 |
| 23 | Jeremy Darvin | Western Ky | SR | DT | 1 | 4 | 1 | 5 | 5.00 |
| 23 | Micah Abraham | Marshall | SO | DB | 1 | 4 | 0 | 4 | 4.00 |
| 33 | Trey Baldwin | La Tech | SR | LB | 1 | 3 | 8 | 11 | 11.00 |
| 33 | Jamal Ligon | UTSA | SO | ILB | 1 | 3 | 5 | 8 | 8.00 |
| 33 | Owen Porter | Marshall | SO | DL | 1 | 3 | 3 | 6 | 6.00 |
| 33 | Damon Miller | UAB | JR | S | 2 | 3 | 3 | 6 | 3.00 |
| 33 | Charlie Gray | Marshall | JR | LB | 1 | 3 | 2 | 5 | 5.00 |
| 33 | Steven Gilmore | Marshall | JR | DB | 1 | 3 | 2 | 5 | 5.00 |
| 33 | Joe Joe Headen | ODU | SR | S | 1 | 3 | 2 | 5 | 5.00 |
| 33 | Kelechi Nwachuku | UTSA | JR | S | 1 | 3 | 2 | 5 | 5.00 |
| 33 | Will Ignont | Western Ky | JR | LB | 1 | 3 | 2 | 5 | 5.00 |
| 33 | Troy Young | UAB | SR | CB | 2 | 3 | 2 | 5 | 2.50 |
| 33 | Dy'jonn Turner | UAB | SR | S | 2 | 3 | 2 | 5 | 2.50 |
| 33 | Rachuan Mitchell | USM | SR | DB | 1 | 3 | 1 | 4 | 4.00 |
| 33 | Starling Thomas V | UAB | JR | CB | 2 | 3 | 1 | 4 | 2.00 |
| 33 | Cedric Woods | La Tech | FR | DB | 1 | 3 | 0 | 3 | 3.00 |
| 33 | Khalil Ladler | La Tech | SR | DB | 1 | 3 | 0 | 3 | 3.00 |
| 33 | Camron Harrell | USM | JR | DB | 1 | 3 | 0 | 3 | 3.00 |
| 33 | Corey Mayfield Jr. | UTSA | SR | CB | 1 | 3 | 0 | 3 | 3.00 |
| 50 | Deshaun Oliver Jr. | UAB | JR | LB | 2 | 2 | 9 | 11 | 5.50 |