2021 Conference USA Leaders Passing - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Bailey Zappe | Western Ky | SR | QB | 5 | 230 | 166 | 72.2 | 2134 | 9.3 | 22 | 2 | 179.93 | 46.0 | 426.8 |
| 2 | Austin Kendall | La Tech | SR | QB | 4 | 145 | 89 | 61.4 | 1178 | 8.1 | 10 | 5 | 145.48 | 36.3 | 294.5 |
| 3 | Grant Wells | Marshall | FR | QB | 5 | 175 | 111 | 63.4 | 1482 | 8.5 | 5 | 6 | 137.14 | 35.0 | 296.4 |
| 4 | N'Kosi Perry | FAU | SR | QB | 4 | 136 | 76 | 55.9 | 949 | 7.0 | 7 | 1 | 130.02 | 34.0 | 237.3 |
| 5 | Max Bortenschlager | FIU | SR | QB | 4 | 116 | 63 | 54.3 | 1105 | 9.5 | 8 | 3 | 151.92 | 29.0 | 276.3 |
| 6 | Frank Harris | UTSA | SR | QB | 5 | 141 | 97 | 68.8 | 1117 | 7.9 | 6 | 1 | 147.95 | 28.2 | 223.4 |
| 7 | D.J. Mack Jr. | ODU | JR | QB | 4 | 110 | 56 | 50.9 | 556 | 5.1 | 3 | 4 | 95.10 | 27.5 | 139.0 |
| 8 | Chris Reynolds | Charlotte | SR | QB | 4 | 98 | 59 | 60.2 | 776 | 7.9 | 7 | 3 | 144.16 | 24.5 | 194.0 |
| 9 | Gavin Hardison | UTEP | SO | QB | 5 | 119 | 67 | 56.3 | 1200 | 10.1 | 7 | 6 | 150.34 | 23.8 | 240.0 |
| 10 | Chase Cunningham | MTSU | JR | QB | 4 | 90 | 57 | 63.3 | 636 | 7.1 | 7 | 1 | 146.14 | 22.5 | 159.0 |
| 11 | Ty Keyes | USM | FR | QB | 3 | 62 | 31 | 50.0 | 338 | 5.5 | 3 | 3 | 102.09 | 20.7 | 112.7 |
| 12 | Austin Aune | N Texas | SO | QB | 5 | 102 | 57 | 55.9 | 814 | 8.0 | 5 | 6 | 127.33 | 20.4 | 162.8 |
| 13 | Dylan Hopkins | UAB | JR | QB | 5 | 81 | 54 | 66.7 | 640 | 7.9 | 7 | 3 | 154.15 | 16.2 | 128.0 |
| 14 | Luke McCaffrey | Rice | FR | QB | 4 | 32 | 16 | 50.0 | 181 | 5.7 | 1 | 3 | 89.07 | 8.0 | 45.3 |
| 15 | Calvin Brownholtz | UTEP | SO | QB | 4 | 7 | 2 | 28.6 | 60 | 8.6 | 1 | 1 | 119.14 | 1.8 | 15.0 |
| 15 | Mike DiLiello | MTSU | SO | QB | 5 | 9 | 3 | 33.3 | 22 | 2.4 | 0 | 1 | 31.64 | 1.8 | 4.4 |
| 17 | Aaron Allen | La Tech | SO | QB | 3 | 2 | 1 | 50.0 | -1 | -0.5 | 0 | 0 | 45.80 | 0.7 | -0.3 |
| 18 | Reynaldo Flores | UTEP | JR | RB | 4 | 1 | 0 | 0.0 | 0 | 0.0 | 0 | 0 | 0.00 | 0.3 | 0.0 |
| 19 | Brenden Brady | UTSA | SR | RB | 5 | 1 | 1 | 100.0 | 8 | 8.0 | 0 | 0 | 167.20 | 0.2 | 1.6 |
| 19 | JaMichael Thompson | MTSU | FR | WR | 5 | 1 | 1 | 100.0 | 5 | 5.0 | 0 | 0 | 142.00 | 0.2 | 1.0 |
| 19 | Xavier Gaines | Marshall | SR | TE | 5 | 1 | 0 | 0.0 | 0 | 0.0 | 0 | 0 | 0.00 | 0.2 | 0.0 |
| 19 | Joshua Cephus | UTSA | JR | WR | 5 | 1 | 0 | 0.0 | 0 | 0.0 | 0 | 0 | 0.00 | 0.2 | 0.0 |
Note: To qualify, player must have played in 75% of his team's games.