2021 Conference USA Leaders Passes Defended - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Naeem Smith | Rice | SR | S | 6 | 3 | 2 | 5 | 0.83 |
| 1 | Beanie Bishop | Western Ky | SO | DB | 6 | 3 | 2 | 5 | 0.83 |
| 3 | Zyon Gilbert | FAU | SR | CB | 6 | 2 | 7 | 9 | 1.50 |
| 3 | Steven Gilmore | Marshall | JR | DB | 6 | 2 | 4 | 6 | 1.00 |
| 3 | Dy'vonne Inyang | UTEP | SR | DB | 5 | 2 | 3 | 5 | 1.00 |
| 3 | Romain Mungin | FAU | SO | CB | 6 | 2 | 3 | 5 | 0.83 |
| 3 | Lakevias Daniel | USM | JR | DB | 6 | 2 | 3 | 5 | 0.83 |
| 3 | Corey Mayfield Jr. | UTSA | SR | CB | 7 | 2 | 3 | 5 | 0.71 |
| 3 | George Nyakwol | Rice | SR | DB | 3 | 2 | 2 | 4 | 1.33 |
| 3 | Quincy Riley | MTSU | FR | CB | 3 | 2 | 1 | 3 | 1.00 |
| 3 | Grayson Cash | UAB | JR | S | 5 | 2 | 1 | 3 | 0.60 |
| 3 | Jahmal Sam | UTSA | SO | S | 5 | 2 | 1 | 3 | 0.60 |
| 3 | BeeJay Williamson | La Tech | SO | DB | 5 | 2 | 0 | 2 | 0.40 |
| 3 | Kirk Lockhart | Rice | SO | S | 6 | 2 | 0 | 2 | 0.33 |
| 3 | Jay Stanley | USM | SO | DB | 6 | 2 | 0 | 2 | 0.33 |
| 3 | Demetrius Cain | Western Ky | SR | LB | 6 | 2 | 0 | 2 | 0.33 |
| 3 | Antonio Parks | UTSA | SR | S | 7 | 2 | 0 | 2 | 0.29 |
| 18 | Starling Thomas V | UAB | JR | CB | 5 | 1 | 7 | 8 | 1.60 |
| 18 | Malik Shorts | USM | SO | DB | 6 | 1 | 5 | 6 | 1.00 |
| 18 | Torey Richardson | UTEP | SO | CB | 6 | 1 | 5 | 6 | 1.00 |
| 18 | Reed Blankenship | MTSU | SR | S | 5 | 1 | 4 | 5 | 1.00 |
| 18 | Tyson Wilson | UTEP | SO | DB | 5 | 1 | 4 | 5 | 1.00 |
| 18 | Tariq Woolen | UTSA | SR | CB | 5 | 1 | 4 | 5 | 1.00 |
| 18 | Korel Smith | FAU | SR | CB | 6 | 1 | 4 | 5 | 0.83 |
| 18 | Jordan Helm | FAU | SR | S | 6 | 1 | 4 | 5 | 0.83 |
| 18 | Teja Young | FAU | SO | S | 6 | 1 | 4 | 5 | 0.83 |
| 18 | Makyle Sanders | N Texas | SR | DB | 6 | 1 | 3 | 4 | 0.67 |
| 18 | Joe Joe Headen | ODU | SR | S | 6 | 1 | 3 | 4 | 0.67 |
| 18 | R'Tarriun Johnson | ODU | JR | S | 6 | 1 | 3 | 4 | 0.67 |
| 18 | Miles McCord | Rice | JR | CB | 6 | 1 | 3 | 4 | 0.67 |
| 18 | Gabe Taylor | Rice | FR | DB | 6 | 1 | 3 | 4 | 0.67 |
| 18 | DQ Thomas | MTSU | SR | LB | 5 | 1 | 2 | 3 | 0.60 |
| 18 | Davion Williams | Western Ky | SO | DB | 5 | 1 | 2 | 3 | 0.60 |
| 18 | Miguel Edwards | Western Ky | SO | DB | 5 | 1 | 2 | 3 | 0.60 |
| 18 | Cory McCoy | Marshall | SR | S | 6 | 1 | 2 | 3 | 0.50 |
| 18 | Tyrice Knight | UTEP | JR | LB | 6 | 1 | 2 | 3 | 0.50 |
| 18 | Kahlef Hailassie | Western Ky | SO | DB | 6 | 1 | 2 | 3 | 0.50 |
| 18 | Omari Alexander | Western Ky | SR | DB | 6 | 1 | 2 | 3 | 0.50 |
| 18 | Christian Gomez | Western Ky | JR | LB | 3 | 1 | 1 | 2 | 0.67 |
| 18 | Teldrick Ross | MTSU | SO | S | 5 | 1 | 1 | 2 | 0.40 |
| 18 | A.J. Brathwaite, Jr. | Western Ky | SO | DB | 5 | 1 | 1 | 2 | 0.40 |
| 18 | Khalil Ladler | La Tech | SR | DB | 6 | 1 | 1 | 2 | 0.33 |
| 18 | Dennis Barnes | UTEP | JR | DB | 6 | 1 | 1 | 2 | 0.33 |
| 18 | Deidrick Stanley II | MTSU | FR | S | 3 | 1 | 0 | 1 | 0.33 |
| 18 | Terreance Ellis | Rice | FR | LB | 3 | 1 | 0 | 1 | 0.33 |
| 18 | Jalen Jackson | MTSU | FR | CB | 4 | 1 | 0 | 1 | 0.25 |
| 18 | Noah Wilder | UAB | SR | LB | 5 | 1 | 0 | 1 | 0.20 |
| 18 | Marley Cook | MTSU | FR | DT | 5 | 1 | 0 | 1 | 0.20 |
| 18 | Harold West | N Texas | FR | DB | 5 | 1 | 0 | 1 | 0.20 |
| 18 | Jaden Hunter | Western Ky | JR | DE | 5 | 1 | 0 | 1 | 0.20 |