2019 Conference USA Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/13/2020
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | North Texas | 1 | 6.0 | 20 | 6.00 |
| 2 | Western Kentucky | 2 | 5.0 | 31 | 2.50 |
| 2 | Louisiana Tech | 2 | 5.0 | 18 | 2.50 |
| 4 | Southern Mississippi | 2 | 4.0 | 26 | 2.00 |
| 4 | UTSA | 2 | 4.0 | 20 | 2.00 |
| 4 | UAB | 1 | 2.0 | 13 | 2.00 |
| 4 | Florida International | 1 | 2.0 | 12 | 2.00 |
| 4 | Florida Atlantic | 1 | 2.0 | 6 | 2.00 |
| 9 | Old Dominion | 2 | 3.0 | 23 | 1.50 |
| 10 | Middle Tennessee | 3 | 4.0 | 40 | 1.33 |
| 11 | Rice | 3 | 3.0 | 16 | 1.00 |
| 11 | Charlotte | 1 | 1.0 | 11 | 1.00 |
| 11 | UTEP | 1 | 1.0 | 5 | 1.00 |