2018 American Athletic Conference Leaders Opponent First Downs - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 2 | 14 | 19 | 6 | 39 | 19.5 |
| 2 | Connecticut | 1 | 15 | 11 | 0 | 26 | 26.0 |
| 2 | Houston | 2 | 15 | 44 | 8 | 67 | 33.5 |
| 4 | East Carolina | 2 | 18 | 30 | 3 | 51 | 25.5 |
| 4 | Tulane | 2 | 18 | 42 | 4 | 64 | 32.0 |
| 6 | UCF | 2 | 20 | 22 | 6 | 48 | 24.0 |
| 7 | Tulsa | 2 | 24 | 15 | 5 | 44 | 22.0 |
| 8 | Memphis | 2 | 26 | 26 | 4 | 56 | 28.0 |
| 9 | Temple | 3 | 27 | 26 | 8 | 61 | 20.3 |
| 9 | SMU | 2 | 27 | 13 | 4 | 44 | 22.0 |
| 11 | South Florida | 2 | 29 | 14 | 5 | 48 | 24.0 |