2018 American Athletic Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Connecticut | 1 | 46 | 341 | 7.41 | 3 | 46.00 | 341.00 |
| 2 | East Carolina | 2 | 63 | 395 | 6.27 | 5 | 31.50 | 197.50 |
| 3 | Cincinnati | 2 | 76 | 368 | 4.84 | 4 | 38.00 | 184.00 |
| 4 | Tulane | 2 | 81 | 305 | 3.77 | 3 | 40.50 | 152.50 |
| 5 | SMU | 2 | 82 | 430 | 5.24 | 5 | 41.00 | 215.00 |
| 6 | UCF | 2 | 85 | 270 | 3.18 | 0 | 42.50 | 135.00 |
| 7 | Memphis | 2 | 90 | 474 | 5.27 | 7 | 45.00 | 237.00 |
| 8 | Houston | 2 | 91 | 249 | 2.74 | 6 | 45.50 | 124.50 |
| 9 | Tulsa | 2 | 100 | 437 | 4.37 | 3 | 50.00 | 218.50 |
| 10 | South Florida | 2 | 105 | 631 | 6.01 | 5 | 52.50 | 315.50 |
| 11 | Temple | 3 | 136 | 530 | 3.90 | 6 | 45.33 | 176.67 |