2018 American Athletic Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulsa | 4 | 730 | 724 | 285 | 1454 | 5.10 | 363.5 |
| 2 | UCF | 4 | 767 | 764 | 293 | 1531 | 5.23 | 382.8 |
| 3 | Cincinnati | 5 | 709 | 832 | 329 | 1541 | 4.68 | 308.2 |
| 4 | East Carolina | 4 | 498 | 1092 | 283 | 1590 | 5.62 | 397.5 |
| 5 | SMU | 4 | 558 | 1093 | 301 | 1651 | 5.49 | 412.8 |
| 6 | Temple | 5 | 833 | 1180 | 398 | 2013 | 5.06 | 402.6 |
| 7 | Navy | 5 | 981 | 1143 | 335 | 2124 | 6.34 | 424.8 |
| 8 | Memphis | 5 | 814 | 1314 | 358 | 2128 | 5.94 | 425.6 |
| 9 | South Florida | 5 | 1190 | 1015 | 371 | 2205 | 5.94 | 441.0 |
| 10 | Tulane | 5 | 834 | 1390 | 379 | 2224 | 5.87 | 444.8 |
| 11 | Connecticut | 4 | 1187 | 1261 | 286 | 2448 | 8.56 | 612.0 |
| 12 | Houston | 5 | 963 | 1641 | 416 | 2604 | 6.26 | 520.8 |