2018 American Athletic Conference Leaders Total Defense - Games vs. Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 8 | 760 | 1645 | 511 | 2405 | 4.71 | 300.6 |
| 2 | Navy | 8 | 1509 | 1910 | 515 | 3419 | 6.64 | 427.4 |
| 3 | Connecticut | 8 | 2833 | 2128 | 555 | 4961 | 8.94 | 620.1 |
| 4 | Tulane | 8 | 1081 | 1983 | 572 | 3064 | 5.36 | 383.0 |
| 5 | East Carolina | 8 | 1539 | 2149 | 576 | 3688 | 6.40 | 461.0 |
| 6 | Tulsa | 8 | 2067 | 1371 | 584 | 3438 | 5.89 | 429.8 |
| 7 | South Florida | 8 | 2028 | 1573 | 623 | 3601 | 5.78 | 450.1 |
| 8 | SMU | 8 | 1799 | 1702 | 630 | 3501 | 5.56 | 437.6 |
| 9 | Temple | 8 | 1574 | 1256 | 638 | 2830 | 4.44 | 353.8 |
| 10 | Houston | 8 | 1914 | 1941 | 669 | 3855 | 5.76 | 481.9 |
| 11 | Memphis | 9 | 1591 | 2275 | 711 | 3866 | 5.44 | 429.6 |
| 12 | UCF | 9 | 2123 | 1984 | 738 | 4107 | 5.57 | 456.3 |