2018 American Athletic Conference Leaders Interceptions - Games vs. Conference Teams Only through 01/07/2019
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Nick Roberts | S Florida | FR | DB | 8 | 3 | 91 | 0 | 0.38 |
| 2 | James Wiggins | Cincinnati | SO | S | 8 | 1 | 86 | 1 | 0.13 |
| 3 | Gleson Sprewell | Houston | SO | DB | 8 | 3 | 71 | 1 | 0.38 |
| 4 | Sean Williams | Navy | SR | S | 8 | 2 | 57 | 0 | 0.25 |
| 5 | Micah Farrar | Navy | SO | CB | 6 | 1 | 54 | 0 | 0.17 |
| 6 | Nick Watkins | Houston | SR | CB | 8 | 2 | 50 | 1 | 0.25 |
| 7 | Donnie Lewis Jr. | Tulane | SR | CB | 8 | 1 | 49 | 1 | 0.13 |
| 8 | Isaiah Johnson | Houston | SR | CB | 7 | 2 | 45 | 0 | 0.29 |
| 9 | Kevin Johnson | SMU | JR | CB | 8 | 2 | 43 | 0 | 0.25 |
| 10 | Arquon Bush | Cincinnati | FR | CB | 2 | 2 | 36 | 1 | 1.00 |
| 10 | Carlito Gonzalez | Memphis | SO | DB | 3 | 1 | 36 | 0 | 0.33 |
| 10 | Ty Mason | Temple | FR | CB | 8 | 1 | 36 | 1 | 0.13 |
| 13 | Cooper Edmiston | Tulsa | JR | LB | 8 | 4 | 34 | 0 | 0.50 |
| 14 | Ronnie Hoggins | S Florida | SR | CB | 8 | 1 | 27 | 0 | 0.13 |
| 15 | Will Harper | Tulane | JR | S | 8 | 1 | 24 | 0 | 0.13 |
| 16 | Patrick Nelson | SMU | JR | S | 8 | 2 | 23 | 0 | 0.25 |
| 17 | Corey Seargent | ECU | SR | DB | 8 | 1 | 22 | 0 | 0.13 |
| 17 | Todd Jones | Temple | SR | LB | 8 | 1 | 22 | 0 | 0.13 |
| 19 | McKinley Whitfield | Tulsa | SR | S | 8 | 1 | 21 | 0 | 0.13 |
| 20 | P.J. Hall | Tulane | JR | S | 7 | 1 | 20 | 0 | 0.14 |
| 21 | Tito Windham | Memphis | SR | DB | 8 | 1 | 18 | 0 | 0.13 |
| 22 | Shaun Bradley | Temple | JR | LB | 8 | 1 | 16 | 0 | 0.13 |
| 23 | Richie Grant | UCF | SO | DB | 9 | 4 | 13 | 0 | 0.44 |
| 24 | Zachery Harris | Tulane | SR | LB | 8 | 1 | 12 | 0 | 0.13 |
| 25 | Taris Shenall | Tulane | SR | S | 8 | 1 | 11 | 0 | 0.13 |
| 26 | Alexander Myres | Houston | SR | CB | 8 | 1 | 9 | 0 | 0.13 |
| 26 | Roman Brown | Houston | SR | LB | 8 | 1 | 9 | 0 | 0.13 |
| 28 | Christian Braswell | Temple | FR | CB | 8 | 1 | 8 | 1 | 0.13 |
| 28 | Deontay Anderson | Houston | SO | DB | 8 | 1 | 8 | 0 | 0.13 |
| 30 | Elijah McQueen | SMU | SO | S | 7 | 1 | 6 | 0 | 0.14 |
| 31 | Tyrell Gilbert | Cincinnati | SR | CB | 7 | 1 | 3 | 0 | 0.14 |
| 32 | Jordan Wyatt | SMU | SR | CB | 6 | 1 | 1 | 0 | 0.17 |