2018 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/07/2019
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina | 1 | 33 | 140 | 4.24 | 2 | 33.00 | 140.00 |
| 2 | Miami (Florida) | 1 | 41 | 156 | 3.80 | 2 | 41.00 | 156.00 |
| 3 | Virginia Tech | 2 | 68 | 423 | 6.22 | 7 | 34.00 | 211.50 |
| 4 | Georgia Tech | 2 | 78 | 533 | 6.83 | 4 | 39.00 | 266.50 |
| 5 | Boston College | 2 | 88 | 337 | 3.83 | 4 | 44.00 | 168.50 |
| 6 | North Carolina State | 3 | 103 | 573 | 5.56 | 12 | 34.33 | 191.00 |
| 7 | Duke | 3 | 115 | 475 | 4.13 | 5 | 38.33 | 158.33 |
| 8 | Syracuse | 3 | 125 | 610 | 4.88 | 6 | 41.67 | 203.33 |
| 9 | Clemson | 4 | 130 | 368 | 2.83 | 2 | 32.50 | 92.00 |
| 10 | Wake Forest | 3 | 140 | 976 | 6.97 | 17 | 46.67 | 325.33 |
| 11 | Louisville | 4 | 180 | 1380 | 7.67 | 18 | 45.00 | 345.00 |
| 12 | Florida State | 4 | 192 | 989 | 5.15 | 9 | 48.00 | 247.25 |
| 13 | Pittsburgh | 5 | 193 | 1009 | 5.23 | 12 | 38.60 | 201.80 |