2018 Conference USA Leaders First Downs - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Florida International | 2 | 10 | 13 | 6 | 29 | 14.5 |
| 2 | Middle Tennessee | 3 | 30 | 26 | 5 | 61 | 20.3 |
| 3 | Old Dominion | 1 | 7 | 19 | 4 | 30 | 30.0 |
| 3 | North Texas | 1 | 3 | 11 | 4 | 18 | 18.0 |
| 5 | UTSA | 3 | 18 | 30 | 3 | 51 | 17.0 |
| 6 | Western Kentucky | 2 | 17 | 22 | 2 | 41 | 20.5 |
| 6 | Florida Atlantic | 1 | 7 | 11 | 2 | 20 | 20.0 |
| 6 | Louisiana Tech | 2 | 15 | 19 | 2 | 36 | 18.0 |
| 6 | Rice | 2 | 17 | 15 | 2 | 34 | 17.0 |
| 6 | Marshall | 2 | 10 | 22 | 2 | 34 | 17.0 |
| 6 | Southern Mississippi | 1 | 2 | 11 | 2 | 15 | 15.0 |
| 6 | Charlotte | 1 | 4 | 7 | 2 | 13 | 13.0 |
| 13 | UTEP | 1 | 4 | 2 | 1 | 7 | 7.0 |
| 14 | UAB | 1 | 9 | 16 | 0 | 25 | 25.0 |