2018 Conference USA Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Charlotte | 1 | 2 | 0 | 2 | 0 | 0 | 14 | 14.0 |
| 2 | North Texas | 1 | 2 | 1 | 2 | 0 | 0 | 17 | 17.0 |
| 3 | Southern Mississippi | 1 | 3 | 1 | 3 | 0 | 0 | 24 | 24.0 |
| 3 | UTEP | 1 | 3 | 1 | 3 | 0 | 0 | 24 | 24.0 |
| 5 | Western Kentucky | 2 | 6 | 4 | 6 | 0 | 0 | 54 | 27.0 |
| 6 | Florida International | 2 | 9 | 2 | 9 | 0 | 0 | 69 | 34.5 |
| 7 | Old Dominion | 1 | 5 | 0 | 5 | 0 | 0 | 35 | 35.0 |
| 8 | Marshall | 2 | 9 | 5 | 9 | 0 | 0 | 78 | 39.0 |
| 9 | Middle Tennessee | 3 | 16 | 2 | 16 | 0 | 0 | 118 | 39.3 |
| 10 | UAB | 1 | 5 | 2 | 5 | 0 | 0 | 41 | 41.0 |
| 11 | Louisiana Tech | 2 | 11 | 2 | 11 | 0 | 0 | 83 | 41.5 |
| 12 | UTSA | 3 | 16 | 5 | 16 | 0 | 0 | 127 | 42.3 |
| 13 | Rice | 2 | 14 | 0 | 14 | 0 | 0 | 98 | 49.0 |
| 14 | Florida Atlantic | 1 | 9 | 0 | 9 | 0 | 0 | 63 | 63.0 |