2018 Conference USA Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Rice | 1 | 180 | 372 | 69 | 552 | 8.00 | 552.0 |
| 2 | North Texas | 1 | 197 | 359 | 83 | 556 | 6.70 | 556.0 |
| 3 | Louisiana Tech | 1 | 218 | 191 | 76 | 409 | 5.38 | 409.0 |
| 4 | UAB | 1 | 252 | 192 | 54 | 444 | 8.22 | 444.0 |
| 5 | Middle Tennessee | 2 | 464 | 344 | 110 | 808 | 7.35 | 404.0 |
| 6 | Florida Atlantic | 2 | 555 | 640 | 144 | 1195 | 8.30 | 597.5 |