2016 American Athletic Conference Leaders Total Defense - Games at Home Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 6 | 412 | 1303 | 417 | 1715 | 4.11 | 285.8 |
| 2 | Temple | 7 | 972 | 985 | 449 | 1957 | 4.36 | 279.6 |
| 3 | UCF | 6 | 1263 | 846 | 462 | 2109 | 4.56 | 351.5 |
| 4 | Cincinnati | 7 | 1248 | 1520 | 535 | 2768 | 5.17 | 395.4 |
| 5 | South Florida | 7 | 1383 | 1746 | 577 | 3129 | 5.42 | 447.0 |
| 6 | Tulsa | 6 | 859 | 1608 | 454 | 2467 | 5.43 | 411.2 |
| 7 | Tulane | 6 | 974 | 1455 | 444 | 2429 | 5.47 | 404.8 |
| 8 | Connecticut | 7 | 798 | 1930 | 483 | 2728 | 5.65 | 389.7 |
| 9 | Memphis | 7 | 1323 | 1968 | 566 | 3291 | 5.81 | 470.1 |
| 10 | East Carolina | 6 | 1389 | 1171 | 419 | 2560 | 6.11 | 426.7 |
| 11 | Navy | 6 | 871 | 1826 | 422 | 2697 | 6.39 | 449.5 |
| 12 | SMU | 6 | 1230 | 1489 | 405 | 2719 | 6.71 | 453.2 |