2016 Atlantic Coast Conference Leaders Rushing Defense - Games in October Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 4 | 123 | 409 | 3.33 | 1 | 30.75 | 102.25 |
| 2 | Boston College | 4 | 112 | 385 | 3.44 | 4 | 28.00 | 96.25 |
| 2 | Florida State | 4 | 130 | 396 | 3.05 | 4 | 32.50 | 99.00 |
| 2 | Miami (Florida) | 5 | 213 | 993 | 4.66 | 4 | 42.60 | 198.60 |
| 5 | North Carolina State | 5 | 186 | 576 | 3.10 | 5 | 37.20 | 115.20 |
| 5 | Virginia | 4 | 150 | 640 | 4.27 | 5 | 37.50 | 160.00 |
| 5 | Wake Forest | 4 | 181 | 719 | 3.97 | 5 | 45.25 | 179.75 |
| 8 | Virginia Tech | 4 | 135 | 451 | 3.34 | 6 | 33.75 | 112.75 |
| 8 | Syracuse | 4 | 167 | 757 | 4.53 | 6 | 41.75 | 189.25 |
| 10 | Duke | 4 | 161 | 874 | 5.43 | 7 | 40.25 | 218.50 |
| 11 | Pittsburgh | 4 | 140 | 581 | 4.15 | 8 | 35.00 | 145.25 |
| 11 | Clemson | 4 | 163 | 719 | 4.41 | 8 | 40.75 | 179.75 |
| 13 | North Carolina | 4 | 184 | 661 | 3.59 | 9 | 46.00 | 165.25 |
| 14 | Georgia Tech | 4 | 156 | 750 | 4.81 | 10 | 39.00 | 187.50 |