2016 Atlantic Coast Conference Leaders Rushing Defense - Games Lost Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 6 | 216 | 788 | 3.65 | 13 | 36.00 | 131.33 |
| 2 | Pittsburgh | 5 | 179 | 694 | 3.88 | 10 | 35.80 | 138.80 |
| 3 | North Carolina | 5 | 269 | 1093 | 4.06 | 11 | 53.80 | 218.60 |
| 4 | Boston College | 6 | 239 | 1060 | 4.44 | 12 | 39.83 | 176.67 |
| 5 | Louisville | 4 | 148 | 671 | 4.53 | 5 | 37.00 | 167.75 |
| 6 | Miami (Florida) | 4 | 159 | 726 | 4.57 | 2 | 39.75 | 181.50 |
| 7 | Virginia Tech | 4 | 190 | 886 | 4.66 | 11 | 47.50 | 221.50 |
| 8 | Clemson | 1 | 33 | 156 | 4.73 | 1 | 33.00 | 156.00 |
| 9 | Wake Forest | 6 | 259 | 1254 | 4.84 | 13 | 43.17 | 209.00 |
| 10 | Duke | 8 | 333 | 1637 | 4.92 | 15 | 41.63 | 204.63 |
| 11 | Virginia | 10 | 420 | 2081 | 4.95 | 17 | 42.00 | 208.10 |
| 12 | Florida State | 3 | 116 | 580 | 5.00 | 11 | 38.67 | 193.33 |
| 13 | Georgia Tech | 4 | 138 | 750 | 5.43 | 11 | 34.50 | 187.50 |
| 14 | Syracuse | 8 | 341 | 2127 | 6.24 | 32 | 42.63 | 265.88 |