2016 Big 12 Conference Leaders Interceptions - Games in August/September Only through 01/09/2017
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Orion Stewart | Baylor | SR | S | 4 | 3 | 58 | 1 | 0.75 |
| 2 | Ramon Richards | Okla St | JR | CB | 4 | 2 | 2 | 0 | 0.50 |
| 2 | Fish Smithson | Kansas | SR | S | 4 | 2 | 0 | 0 | 0.50 |
| 4 | Rasul Douglas | WVU | SR | CB | 3 | 1 | 54 | 1 | 0.33 |
| 4 | Kendall Adams | Kansas St | SO | DB | 3 | 1 | 15 | 0 | 0.33 |
| 4 | Al-Rasheed Benton | WVU | JR | LB | 3 | 1 | 13 | 0 | 0.33 |
| 4 | Maurice Fleming | WVU | SR | CB | 3 | 1 | 2 | 0 | 0.33 |
| 4 | D.J. Reed | Kansas St | SO | DB | 3 | 1 | 0 | 0 | 0.33 |
| 4 | Matt Seiwert | Kansas St | JR | DT | 3 | 1 | 0 | 0 | 0.33 |
| 4 | Keenon Ward | Texas Tech | SR | DB | 3 | 1 | 0 | 0 | 0.33 |
| 4 | Jeremy Tyler | WVU | SR | S | 3 | 1 | 0 | 0 | 0.33 |
| 12 | Davion Hall | Baylor | JR | S | 4 | 1 | 62 | 0 | 0.25 |
| 12 | Jomal Wiltz | Iowa State | SR | DB | 4 | 1 | 27 | 0 | 0.25 |
| 12 | Nick Orr | TCU | JR | S | 4 | 1 | 12 | 0 | 0.25 |
| 12 | Jarnor Jones | Iowa State | SR | DB | 4 | 1 | 11 | 0 | 0.25 |
| 12 | Brian Peavy | Iowa State | SO | DB | 4 | 1 | 4 | 0 | 0.25 |
| 12 | Kamari Cotton-Moya | Iowa State | JR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Bazie Bates IV | Kansas | SR | S | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Jordan Burton | Okla St | SR | LB | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Niko Small | TCU | SO | S | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Jah'Shawn Johnson | Texas Tech | SO | DB | 4 | 1 | 0 | 0 | 0.25 |
| 12 | Thierry Nguema | Texas Tech | SR | DB | 4 | 1 | 0 | 0 | 0.25 |
Note: To qualify, player must have played in 75% of his team's games.