2016 Conference USA Leaders Passing Defense - Games in August/September Only through 01/09/2017
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 4 | 94 | 44 | 46.8 | 579 | 6.2 | 7 | 4 | 114.62 | 23.5 | 144.8 |
| 2 | UTEP | 4 | 104 | 63 | 60.6 | 801 | 7.7 | 8 | 0 | 150.66 | 26.0 | 200.3 |
| 3 | Florida International | 4 | 111 | 73 | 65.8 | 981 | 8.8 | 8 | 1 | 161.99 | 27.8 | 245.3 |
| 4 | UTSA | 4 | 112 | 57 | 50.9 | 721 | 6.4 | 5 | 1 | 117.91 | 28.0 | 180.3 |
| 4 | Rice | 4 | 112 | 70 | 62.5 | 1184 | 10.6 | 7 | 1 | 170.14 | 28.0 | 296.0 |
| 6 | North Texas | 4 | 115 | 61 | 53.0 | 826 | 7.2 | 4 | 4 | 117.90 | 28.8 | 206.5 |
| 7 | Old Dominion | 4 | 128 | 77 | 60.2 | 926 | 7.2 | 6 | 3 | 131.71 | 32.0 | 231.5 |
| 8 | Florida Atlantic | 4 | 140 | 91 | 65.0 | 999 | 7.1 | 5 | 3 | 132.43 | 35.0 | 249.8 |
| 9 | Louisiana Tech | 4 | 142 | 87 | 61.3 | 1154 | 8.1 | 11 | 2 | 152.28 | 35.5 | 288.5 |
| 10 | Middle Tennessee | 4 | 143 | 78 | 54.5 | 800 | 5.6 | 4 | 3 | 106.57 | 35.8 | 200.0 |
| 11 | Marshall | 3 | 109 | 60 | 55.0 | 971 | 8.9 | 9 | 2 | 153.46 | 36.3 | 323.7 |
| 12 | Charlotte | 4 | 148 | 96 | 64.9 | 1295 | 8.8 | 12 | 4 | 159.72 | 37.0 | 323.8 |
| 13 | Western Kentucky | 4 | 150 | 86 | 57.3 | 1155 | 7.7 | 5 | 3 | 129.01 | 37.5 | 288.8 |